3.A.6.1.1
Type III protein secretion complex. Assembly of the YscR,S,T,U,V complex occurs independently of other structural components and involves the formation of a YscV oligomer (Diepold et al., 2011). A C-terminal region of Yersinia pestis YscD binds the outer membrane secretin YscC (Ross and Plano, 2011). YopBD-mediated translocation of T3SS cargo, but not YopBD pore formation, leads to activation of host pathways influencing inflammation, cell death, and response to stress (Kwuan et al. 2013).
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| Accession Number: | Q93KT6 |
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| Protein Name: | YscP |
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| Length: | 453 |
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| Molecular Weight: | 50655.00 |
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| Species: | Yersinia enterocolitica [630] |
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| Location1 / Topology2 / Orientation3: |
Cytoplasm1 / Peripheral membrane protein2 |
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| Substrate |
protein polypeptide chain |
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| RefSeq: |
NP_863525.1
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| Entrez Gene ID: |
1449469
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| Pfam: |
PF02120
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[1] “Complete DNA sequence of Yersinia enterocolitica serotype 0:8 low-calcium-response plasmid reveals a new virulence plasmid-associated replicon.” Snellings N.J. et.al. 11402007
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1: MNKITTRSPL EPEYQPLGKP HHDLQARVDF EQALLHNKDN RHPKEEPRRP VRPHDLGKKE
61: GQKGDGLRAH APLAATFQPG REVGLKPQHN HQNNHDFNLS PLAEGATNRK HLYQQDSRFD
121: DRVESIINAL MPLAPFLEGV TCETGTSSES PCEPFGHDEL FVQQSPIDSA QPVQLNTKPT
181: VQSLNPAADG AEVMIWSVGR DTLASIAKNQ RDSRQKRLAE EPLPLHQEAL PEVCPPAVST
241: TPDDHLVARW CATPVAEVAE KSARFPHKAT VQSEQLDMTE LADRSQHLTD GVDSSKDTIE
301: PPRPEELLLP REETLPEMYS LSFTAPVITP GDHLLATMRA TRLASVSEQL IQLAQRLAVE
361: LELRGGSSQV TQLHLNLPEL GAIMVRIAEI PGKLHVELIA SRETLRILAQ GSYDLLERLQ
421: RIEPTQLDFQ ASGDSEQESR QKRHVYEEWE AEE