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3.D.9.1.1 F₄₂₀H₂ dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F₄₂₀:phenazine oxidoreductase) (Welte and Deppenmeier 2013). Found in both Euryarchaota and Bathyarchaeota (Evans et al. 2015).
Accession Number:	Q9P9F3
Protein Name:	FpoN aka MM2480
Length:	493
Molecular Weight:	52716.00
Species:	Methanosarcina mazei (Methanosarcina frisia) [2209]
Number of TMSs:	13
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	hydron

RefSeq:	NP_634504.1
Entrez Gene ID:	1480822
Pfam:	PF00361
BioCyc:	MMAZ192952:MM2480-MONOMER
KEGG:	mma:MM_2480
Gene Ontology GO:0008137 F:NADH dehydrogenase (ubiquinone) activity GO:0042773 P:ATP synthesis coupled electron transport
References (2) [1] “The F(420)H(2) dehydrogenase from Methanosarcina mazei is a redox-driven proton pump closely related to NADH dehydrogenases.” Baeumer S.et.al. 10751389 [2] “The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea.” Deppenmeier U.et.al. 12125824

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MQEIMYLAPE LVLVATGLVI LLTGVFLSPQ SKNILGYLAT LGTLAAIFLT VKSFGLLTME 
61:	GFSVQYTIFS ETLSIDALSQ FFKLVFLAVA LIVSIASIKY TENSDHTEEF YTLVLFATFG 
121:	MMIVASANDL ILLFCAFELA SLATFALAGF EKQNARSLEG AMKYFVIGSV SAALMLFGLS 
181:	FVYGATGTTS IPLIAQNPGL LTGNPIGIVA IVLLTAGFGF KMALVPFHMW APDTYQGSPS 
241:	VVSALLAAGS KKMGFVAAFR VFIIALAALQ PDWQFMFTLL AVVTMTFGNV VAVAQTSVKR 
301:	MLAYSSLAQA GYIAMAFAVM TPVALAGGIM YTLAHAFMKA GAFIAAAAVV WMITSEKTGN 
361:	LDIPDHLDSF RGLGKRMPLA ALCMTVFVFA LAGIPPTAGF MAKFVLFSST IQAGMTWLAV 
421:	IAILNSALSL FYYARLVKYM YFMPPEGKTE KVSIPFPYAA ALLVAVAGVL VMGLWPEPFV 
481:	ELAMKAAMVL VPF

3.D.9.1.1
F₄₂₀H₂ dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F₄₂₀:phenazine oxidoreductase) (Welte and Deppenmeier 2013). Found in both Euryarchaota and Bathyarchaeota (Evans et al. 2015).

Cross database links:

Gene Ontology

References (2)

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3.D.9.1.1F420H2 dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F420:phenazine oxidoreductase) (Welte and Deppenmeier 2013). Found in both Euryarchaota and Bathyarchaeota (Evans et al. 2015).

Cross database links:

Gene Ontology

References (2)

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3.D.9.1.1
F₄₂₀H₂ dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F₄₂₀:phenazine oxidoreductase) (Welte and Deppenmeier 2013). Found in both Euryarchaota and Bathyarchaeota (Evans et al. 2015).