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3.D.9.1.1 F₄₂₀H₂ dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F₄₂₀:phenazine oxidoreductase) (Welte and Deppenmeier 2013). Found in both Euryarchaota and Bathyarchaeota (Evans et al. 2015).
Accession Number:	Q9P9F5
Protein Name:	FpoL aka MM2482
Length:	672
Molecular Weight:	72393.00
Species:	Methanosarcina mazei (Methanosarcina frisia) [2209]
Number of TMSs:	18
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	hydron

RefSeq:	NP_634506.1
Entrez Gene ID:	1480824
Pfam:	PF00361 PF00662
BioCyc:	MMAZ192952:MM2482-MONOMER
KEGG:	mma:MM_2482
Gene Ontology GO:0008137 F:NADH dehydrogenase (ubiquinone) activity GO:0042773 P:ATP synthesis coupled electron transport
References (2) [1] “The F(420)H(2) dehydrogenase from Methanosarcina mazei is a redox-driven proton pump closely related to NADH dehydrogenases.” Baeumer S.et.al. 10751389 [2] “The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea.” Deppenmeier U.et.al. 12125824

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MVKTALEEFA FLIPLLPALA FAITFFFGRK MPSGGAIVPI LAIAASFVIS FAITLGLLAN 
61:	PEEVISQSYS WFAVLNIGIL IDPLAAVMLS MVSFVSLLIH IYAVSYMSHD AGKARYFAET 
121:	ALFTAAMLSL VLSDNILQLF VSWELVGLCS YLLIGFWFEK PSAAAAAKKA FLTTRIGDVM 
181:	FLTGIIVLTS DLLKVSGGFQ DGVYLLRFDE IFSYIPELAA LQINILGFEI SHLTIITLLF 
241:	FGGAVGKSGQ FPLHVWLPDA MEGPTTVSAL IHAATMVTAG VYLVARTFPM FIAAPDSLMV 
301:	VAYFGGFTAL FAGTMGIVMN DLKRVLAFST ISQLGYMMLG LGLGTAIGLE AVGISLFHLI 
361:	NHAFFKALLF LCAGSVIHAV GTQDMRELGG VGKVMPITAA TMTIAALALA GFGIPGTSIG 
421:	TSGFMSKDPI IEAAYLFGEH SSNWIPYVFS ILAALLTSIY IFRLIFMTFT GKPRSNYHGH 
481:	ESPAIMTIPL SILAIFALAF GALTRTGFME FLEETFTNSF VNLDIGALAG IGENELVAAA 
541:	GHEPLAVLWP PVIVALAGFA IAFVIYYLRA FSLGPLASMK NPIYRLLYNR YYQHQIYTEF 
601:	FSIGIVYGII AFLTQVVDVI IDSVVEGIGI VTVFVGEELR KIQTGVVQTY ATALIAGVSL 
661:	LIILVKLIME VL

3.D.9.1.1
F₄₂₀H₂ dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F₄₂₀:phenazine oxidoreductase) (Welte and Deppenmeier 2013). Found in both Euryarchaota and Bathyarchaeota (Evans et al. 2015).

Cross database links:

Gene Ontology

References (2)

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3.D.9.1.1F420H2 dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F420:phenazine oxidoreductase) (Welte and Deppenmeier 2013). Found in both Euryarchaota and Bathyarchaeota (Evans et al. 2015).

Cross database links:

Gene Ontology

References (2)

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3.D.9.1.1
F₄₂₀H₂ dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F₄₂₀:phenazine oxidoreductase) (Welte and Deppenmeier 2013). Found in both Euryarchaota and Bathyarchaeota (Evans et al. 2015).