TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.D.9.1.1
F420H2 dehydroxygenase, FpoABCFDHIJKLMNO (Fpo = F420:phenazine oxidoreductase) (Welte and Deppenmeier 2013).  Found in both Euryarchaota and Bathyarchaeota (Evans et al. 2015).

Accession Number:Q9P9G2
Protein Name:FpoB aka MM2490
Length:184
Molecular Weight:20732.00
Species:Methanosarcina mazei (Methanosarcina frisia) [2209]
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate hydron

Cross database links:

RefSeq: NP_634514.1   
Entrez Gene ID: 1480832   
Pfam: PF01058   
BioCyc: MetaCyc:MONOMER-12224    MMAZ192952:MM2490-MONOMER   
KEGG: mma:MM_2490   

Gene Ontology

GO:0051539 F:4 iron, 4 sulfur cluster binding
GO:0046872 F:metal ion binding
GO:0008137 F:NADH dehydrogenase (ubiquinone) activity
GO:0048038 F:quinone binding
GO:0055114 P:oxidation reduction

References (2)

[1] “The F(420)H(2) dehydrogenase from Methanosarcina mazei is a redox-driven proton pump closely related to NADH dehydrogenases.”  Baeumer S.et.al.   10751389
[2] “The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea.”  Deppenmeier U.et.al.   12125824

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MGEVKETKTN NSKENPEEEV PGVITTTTSA IHNFLKKTKA QDIINWGRKN SLWFMTQPMG 
61:	CCGVEMIATG CAHYDTDRFG IIPRNSPRHA DVMIISGYVT KKYLPALKRL WDQMPAPKWV 
121:	IAMGDCAISG GPFYESYSTV QNIDEIFPID VYIPGCPPRP EALIQGFVEL QEKIKARKDR 
181:	GTEY