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3.A.7.8.1
Competence system for DNA uptake (ComB) (Hofreuter et al., 2003; Karnholz et al., 2006). DNA uptake into the periplasm occurs preferentially at the poles. Transport into the cytoplasm depends on ComEC. Thus, DNA uptake may occur in a two step process (Stingl et al., 2010).

Accession Number:Q9R823
Protein Name:ComB3
Length:376
Molecular Weight:41945.00
Species:Helicobacter pylori (Campylobacter pylori)   [210]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate DNA

Cross database links:

Pfam: PF03743   

References (1)

[1] “Natural competence for DNA transformation in Helicobacter pylori: identification and genetic characterization of the comB locus.”  Hofreuter D.et.al.   9663688

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNKWLKGVIV FIGGFATITT ISLVYHQKPK APLNNQPSLL NDDEVKYPLQ DYTFTQNPQP 
61:	TNTESSKDAT IKALQEQLKA ALKALNSKEM NYSKEETFKS PPIDPNTTPP KKDFSLKQLD 
121:	LLAARITPFK QSPKNYEENL IFPVDNPKGI DGFTNLKEKD IATNENKLLR TITADKMIPA 
181:	FLITPISSQI AGKVIAQVES DIFAHMGKAV LIPKGSKVIG YYSNNNKMGE YRLDIVWSRI 
241:	ITPHGINIML TNAKGADIKG YNGLVGELIE RNFQRYGVPL LLSTLTNGLL IGITSALNNR 
301:	GNKEGATNFF GDYLLMQLMR QSGMGINQVV NQILRDKSKI APIVVIREGS RVFISPNTDI 
361:	FFPIPRENEV IAEFLK