3.A.7.8.1 Competence system for DNA uptake (ComB) (Hofreuter et al., 2003; Karnholz et al., 2006). DNA uptake into the periplasm occurs preferentially at the poles. Transport into the cytoplasm depends on ComEC. Thus, DNA uptake may occur in a two step process (Stingl et al., 2010).
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Accession Number: | Q9R823 |
Protein Name: | ComB3 |
Length: | 376 |
Molecular Weight: | 41945.00 |
Species: | Helicobacter pylori (Campylobacter pylori) [210] |
Number of TMSs: | 3 |
Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate |
deoxyribonucleic acid |
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Pfam: |
PF03743
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[1] “Natural competence for DNA transformation in Helicobacter pylori: identification and genetic characterization of the comB locus.” Hofreuter D. et.al. 9663688
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1: MNKWLKGVIV FIGGFATITT ISLVYHQKPK APLNNQPSLL NDDEVKYPLQ DYTFTQNPQP
61: TNTESSKDAT IKALQEQLKA ALKALNSKEM NYSKEETFKS PPIDPNTTPP KKDFSLKQLD
121: LLAARITPFK QSPKNYEENL IFPVDNPKGI DGFTNLKEKD IATNENKLLR TITADKMIPA
181: FLITPISSQI AGKVIAQVES DIFAHMGKAV LIPKGSKVIG YYSNNNKMGE YRLDIVWSRI
241: ITPHGINIML TNAKGADIKG YNGLVGELIE RNFQRYGVPL LLSTLTNGLL IGITSALNNR
301: GNKEGATNFF GDYLLMQLMR QSGMGINQVV NQILRDKSKI APIVVIREGS RVFISPNTDI
361: FFPIPRENEV IAEFLK