4.A.1.1.20
The N-acetylglucosamine PTS transporter/kinase, NagE2 (416 aas; IIC)/NagF (77 aas; IIB). The IIA specific for glucose (Crr) is the IIA for this system, and activity depends on Enzyme I and HPr (Nothaft et al. 2010). The genes encoding these enzymes are regulated by two transcription factors, DasR and AtrA, and the system serves as a sensor as well as a transporter/kinase (Nothaft et al. 2010).
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| Accession Number: | Q9S2H4 |
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| Protein Name: | Putative PTS transmembrane component |
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| Length: | 416 |
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| Molecular Weight: | 44168.00 |
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| Species: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226] |
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| Number of TMSs: | 12 |
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| Substrate |
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1: MSTATDTAAP AKKRGSGLFQ GLQKVGRSLQ LPIAVLPAAG IMVRLGQDDI FGKDGLGWDK
61: VAAVFNNAGG ALTGSLPILF CIGVAIGFAK KADGSTALAA VVGFLVYSKV LEAFPVTEAV
121: VQDGADVAAT YNDPGVLGGI IMGLLAAVLW QRYHRKKLVD WLGFFNGRRL VPIIMAFVGI
181: VVGVFFGLVW EPIGDGISNF GEWMTGLGSG GAALFGGVNR ALIPVGMHQF VNTVAWFQLG
241: DFTNSAGDVV HGDITRFLAG DPSAGIFQAG FFPIMMFGLP AAALAMAHTA RPERRKAVLG
301: MMISLAATSF VTGVTEPIEF SFMFIAPVLY VLHAVLTAIS MAITWGLGVH AGFNFSAGFI
361: DYALNWHLAT KPWLIIPIGL VFAAIYYVTF RFAIVKFNLK TPGREPEEEV EDLTKA