3.A.1.14.7
Iron (Fe3+)-hydroxamate porter (transports Fe3+-ferrichrome and Fe3+-ferrioxamine B with FhuD1, and these compounds plus aerobactin and coprogen with FhuD2). FhuB may function with FhuG (A6QEV8) together with FhuD2 to form a ferrichrome transporter where FhuB and FhuG have conserved arginine residues (R71 and R61, respectively) that form essential salt bridges with FhuD2 (Vinés et al. 2013).
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| Accession Number: | Q9X665 |
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| Protein Name: | FhuC aka FhuA |
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| Length: | 265 |
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| Molecular Weight: | 29496.00 |
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| Species: | Staphylococcus aureus [1280] |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
iron(III) hydroxamate |
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| Pfam: |
PF00005
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[1] “Molecular characterization of the ferric-uptake regulator, Fur, from Staphylococcus aureus.” Xiong A. et.al. 10746769
[2] “Identification and characterization of a membrane permease involved in iron-hydroxamate transport in Staphylococcus aureus.” Sebulsky M.T. et.al. 10913070
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1: MNRLHGQQVK IGYGDNTIIN KLDVEIPDGK VTSIIGPNGC GKSTLLKALS RLLAVKEGEV
61: FLDGENIHTQ STKEIAKKIA ILPQSPEVAD GLTVGELVSY GRFPHQKGFG RLTAEDKKEI
121: DWAMEVTGTD TFRHRSINDL SGGQRQRVWI AMALAQRTDI IFLDEPTTYL DICHQLEILE
181: LVQKLNQEQG CTIVMVLHDI NQAIRFSDHL IAMKEGDIIA TGSTEDVLTQ EILEKVFNID
241: VVLSKDPKTG KPLLVTYDLC RRAYS