3.D.4.4.5
Cytochrome oxidase complex, CtaCDEF with CtaC being subunit 2 or Cox2 (319 aas and 3 TMSs), CtaD being subunit 1 or Cox1 (578 aas and 12 TMSs), CtaE being subunit 3 or Cox3 (206 aas and 5 TMSs), and CtaF being subunit 4 or Cox4 (132 aas with 4 TMSs in a 2 + 2 TMS arrangement). This complex forms a supercomplex with QcrABC (TC# 3.D.3.5.4) (Falke et al. 2018). The supercomplex is required for nitrate reductase 1 activity and is encoded within a single gene cluster (Falke et al. 2019).
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| Accession Number: | Q9X813 |
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| Protein Name: | Probable cytochrome c oxidase subunit 1-alpha |
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| Length: | 578 |
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| Molecular Weight: | 64122.00 |
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| Species: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
hydron |
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1: MSILNEPQGA SAAEDSYENE LPVRRKQPGN VVIKWLTTTD HKTIGTMYLV TSFAFFVIGG
61: VMALFMRAEL ARPGLQIMSN EQFNQAFTMH GTIMLLMFAT PLFAGFANWI MPLQIGAPDV
121: AFPRLNMFAY WLYLFGSTIA VGGFLTPQGA ADFGWFAYSP LSDAVHSPGI GGDLWIMGLA
181: FSGFGTILGS VNFITTIICM RAPGMTMFRM PIFTWNVLLT GVLVLLAFPV LAAALFALEA
241: DRKFGAHIFD SSNGGALLWQ HLFWFFGHPE VYIIALPFFG IVSEIIPVFS RKPIFGYMGL
301: IGATIAIAGL SVTVWAHHMY VTGGVLLPFF SFMTFLIAVP TGVKFFNWIG TMWKGSLSFE
361: TPMLWSTGFL ITFLFGGLTG VILASPPLDF HVSDSYFVVA HFHYVVFGTV VFAMFAGFHF
421: WWPKFTGKML DERLGKITFW TLFVGFHGTF LVQHWLGAEG MPRRYADYLA ADGFTALNTI
481: STISSFLLGM SILPFFYNIW KTAKYGKKIE VDDPWGYGRS LEWATSCPPP RHNFLTLPRI
541: RSESPAFDLH HPEISAIDQL ENVGHGEKAL AGGKEAGK