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3.D.4.4.5
Cytochrome oxidase complex, CtaCDEF with CtaC being subunit 2 or Cox2 (319 aas and 3 TMSs), CtaD being subunit 1 or Cox1 (578 aas and 12 TMSs), CtaE being subunit 3 or Cox3 (206 aas and 5 TMSs), and CtaF being subunit 4 or Cox4 (132 aas with 4 TMSs in a 2 + 2 TMS arrangement). This complex forms a supercomplex with QcrABC (TC# 3.D.3.5.4) (Falke et al. 2018). The supercomplex is required for nitrate reductase 1 activity and is encoded within a single gene cluster (Falke et al. 2019).

Accession Number:Q9X814
Protein Name:Probable cytochrome c oxidase subunit 2
Length:319
Molecular Weight:35447.00
Species:Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate hydron

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSPNGSDRSP RRPMRRKLLQ ALTAGLVLAT ATGCTYEDFP RLGMPTPTTE EAPRILSLWQ 
61:	GSWAAALATG VLVWGLILWS VFFHRRSRTK VEVPPQTRYN LPIEALYTMV PLVIVSVLFY 
121:	FTARDESDLM SLNKKPDLTV NVVGFQWSWC FNHIEDVPGS TGDAKTSKEL AGIPDRFIED 
181:	FPANAGGVYD CGTPGTENPQ TGNPGPTLWL PKGKTVRFVL TSRDVIHSFW VVPFLMKQDV 
241:	IPGHTNAFEV TPNKEGTFLG KCAELCGVDH SRMLFNVKVV SPERYEQHLQ DLAKKGQTGY 
301:	VPAGIAQTSH EKNRETNNL