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3.A.1.119.2
Tetracycline/oxytetracycline/oxacillin exporter, TetAB

Accession Number:Q9Z4Q1
Protein Name:StrA aka TetA
Length:513
Molecular Weight:53711.00
Species:Corynebacterium striatum [43770]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate tetracycline, oxytetracycline, oxacillin

Cross database links:

RefSeq: NP_862226.1   
Entrez Gene ID: 1403746   
Pfam: PF00664    PF00005   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (3)

[1] “The Corynebacterium xerosis composite transposon Tn5432 consists of two identical insertion sequences, designated IS1249, flanking the erythromycin resistance gene ermCX.”  Tauch A.et.al.   8559800
[2] “The tetAB genes of the Corynebacterium striatum R-plasmid pTP10 encode an ABC transporter and confer tetracycline, oxytetracycline and oxacillin resistance in Corynebacterium glutamicum.”  Tauch A.et.al.   10220896
[3] “The 51,409-bp R-plasmid pTP10 from the multiresistant clinical isolate Corynebacterium striatum M82B is composed of DNA segments initially identified in soil bacteria and in plant, animal, and human pathogens.”  Tauch A.et.al.   10732668

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKTYSWFVPP APPADDPARL HPARWSSGNR VVRDMVGAYP GVLVLHILSY LIGSGISAFV 
61:	PVVVGMIVDG LVGEEKFNAW WLFAVLVGIF IIQFIGEATG DGLATASVRR VTHNAQQHLS 
121:	SGVLRRGAGA MSPGTVLNTI DADANTVGRY RELLSFPLMA IGYAVCAMVA MWSVSPWISL 
181:	AIPASALIIA LFAAWTAGPV TRVSLKRRAA EADVAGLATD ASQGIRTVKG LGAGATVATR 
241:	FHAETAKANG LMLTHLRVEV WLGFARFCVA WLCNLGIVGL SAWMTLRGEI TPGQLTSVAL 
301:	LVQPALTMAG LAFGDLASGW GRAVASGQRI EQLHHAGDDA AGPEPTDTPV PGAGLWILEP 
361:	AERSYATAAA WAQRADVLFP PHTVNVFEGT IADNVNPRGD VPEDVVKQAL AAAHCQDILR 
421:	RLGGINEAGE LPDAPLGEAG LNLSGGQRQR VALARALAAD PEVLILDDPT TGLDSVTQAD 
481:	VVAAVAALRA DKTTVVITGN AAWQHAGTEL EVA