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3.A.1.119.2
Tetracycline/oxytetracycline/oxacillin exporter, TetAB

Accession Number:Q9Z4Q2
Protein Name:StrB aka TetB
Length:528
Molecular Weight:55922.00
Species:Corynebacterium striatum [43770]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate tetracycline, oxytetracycline, oxacillin

Cross database links:

RefSeq: NP_862227.1   
Entrez Gene ID: 1403747   
Pfam: PF00664    PF00005   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (3)

[1] “The Corynebacterium xerosis composite transposon Tn5432 consists of two identical insertion sequences, designated IS1249, flanking the erythromycin resistance gene ermCX.”  Tauch A.et.al.   8559800
[2] “The tetAB genes of the Corynebacterium striatum R-plasmid pTP10 encode an ABC transporter and confer tetracycline, oxytetracycline and oxacillin resistance in Corynebacterium glutamicum.”  Tauch A.et.al.   10220896
[3] “The 51,409-bp R-plasmid pTP10 from the multiresistant clinical isolate Corynebacterium striatum M82B is composed of DNA segments initially identified in soil bacteria and in plant, animal, and human pathogens.”  Tauch A.et.al.   10732668

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAPDYARTDA VAPASVKETF AYLSALPNAL DRRWWAGLLL IQALIVAVYT TQSNLFGRSV 
61:	DPLTGGEVPL LGTGTRAFVW TVGLALACML VEMFLRALGN YVVGLKVARA SIDLRRRCLD 
121:	AILRAPVPRV MELGTGNVIT RMTKDIDDVV QTITAIGSRV LTTVFVFPIT FIGLLLIDVR 
181:	FALILLLICI CTYPFARAVV RAIPDASNAV SVAEARRNAV LLDTVRGLPT LRAFDLERWA 
241:	LARMRRTSWG AVEAEMDRVH WFIRLTGIGQ VAFAAWVLLT LGVGAWLASA GVVTRAAQRA 
301:	GRPLCHARGG TTTALVGTSG AGKSTLAALI AGLVEPTAGS IRVGAVETSQ VSDTWTAKNV 
361:	TLLTQDVHLF AGTLREDLSM AAQDATDADL LRALASVGLD PEGTQFARLF PKGLDTAVGA 
421:	GAEDIPPEVE QQLALARVAL SGPKVLILDE ATAEAGSDAT NALEDAAARI TADTTALVVA 
481:	HRLDQAAAAD RILVMDAGRI IEDGTHTELV AADGRYAQLF AAWSGGGH