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3.A.7.8.1
Competence system for DNA uptake (ComB) (Hofreuter et al., 2003; Karnholz et al., 2006). DNA uptake into the periplasm occurs preferentially at the poles. Transport into the cytoplasm depends on ComEC. Thus, DNA uptake may occur in a two step process (Stingl et al., 2010).

Accession Number:Q9ZEL0
Protein Name:ComB1 protein
Length:247
Molecular Weight:28738.00
Species:Helicobacter pylori [210]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate deoxyribonucleic acid

Cross database links:

Pfam: PF04335   

References (1)

[1] “Natural competence for DNA transformation in Helicobacter pylori: identification and genetic characterization of the comB locus.”  Hofreuter D.et.al.   9663688

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MREKPFNSEQ LIYLEELLSH QEKHLENKLS GFSVSDLDMQ SVFRLERNRL KIAYKLLGLM 
61:	SFIALILAIV LISLLPLQKT EHHFVDFLNQ DKHYAIIQRA DKSISSNEAL ARSLIGAYVL 
121:	NRESINRIDD KSRYELVRLQ SSSKVWQRFE DLIKTQNSIY VQSHLEREVH IVNIAIYQQD 
181:	NNPIASVSIA AKLLNENKLV YEKRYKIVLS YLFDTPDFDY ASMPKNPTGF KITRYSITEI 
241:	APTNRGD