3.A.7.8.1 Competence system for DNA uptake (ComB) (Hofreuter et al., 2003; Karnholz et al., 2006). DNA uptake into the periplasm occurs preferentially at the poles. Transport into the cytoplasm depends on ComEC. Thus, DNA uptake may occur in a two step process (Stingl et al., 2010).
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Accession Number: | Q9ZEL0 |
Protein Name: | ComB1 protein |
Length: | 247 |
Molecular Weight: | 28738.00 |
Species: | Helicobacter pylori [210] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
deoxyribonucleic acid |
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Pfam: |
PF04335
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[1] “Natural competence for DNA transformation in Helicobacter pylori: identification and genetic characterization of the comB locus.” Hofreuter D. et.al. 9663688
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1: MREKPFNSEQ LIYLEELLSH QEKHLENKLS GFSVSDLDMQ SVFRLERNRL KIAYKLLGLM
61: SFIALILAIV LISLLPLQKT EHHFVDFLNQ DKHYAIIQRA DKSISSNEAL ARSLIGAYVL
121: NRESINRIDD KSRYELVRLQ SSSKVWQRFE DLIKTQNSIY VQSHLEREVH IVNIAIYQQD
181: NNPIASVSIA AKLLNENKLV YEKRYKIVLS YLFDTPDFDY ASMPKNPTGF KITRYSITEI
241: APTNRGD