3.A.1.126.5 Polyether inonophore exporter, NarAB: NarA, ATPase (C) of 293 aas and NarB, membrane protein (M) of 537 aas and 12 TMSs. The polyether ionophores, narasin, salinomycin, and maduramicin, but not monensin, are actively exported (A-O Naemi et al., NarAB Is an ABC-type Transporter That Confers Resistance to the
Polyether Ionophores Narasin, Salinomycin, and Maduramicin, but Not
Monensin, 2020 Front Microbiol.).
|
Accession Number: | QHA94808.1 |
Protein Name: | QHA94808.1 NarA [Enterococcus faecium] |
Length: | 294 |
Molecular Weight: | |
Species: | Enterococcus faecium [1352] |
Number of TMSs: | 1 |
Substrate |
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1: MTEIVKVQGL QKKFGKFQAL KDVSFTVNAG EVVGFIGPNG AGKSTTIRTL LGIINRDEGD
61: VQIFGKDVWK DSLEIHKRIS YVPGDVALWG SLTGGEIIDL FIKLHGGGSK AKRDYLIKRF
121: ELDPKKKAKG YSKGNRQKVG LIAALSVESD LYILDEPTSG LDPLMEAVFQ EEVEKIKNDG
181: KAILLSSHIL SEVERLADKV AIIRRGEVVE TGTLDELRHL TRSTVTLVTK GDIEKLATLS
241: GVHDFVQKDG KATFSADNEA MNTILTEATK LGVIKIESVP PTLEDLFMRH YEG