3.A.1.5.50
Peptide transporter, OppABCD of 591, 325, 291 and 612 aas with 1, 6, 6, and 0 TMSs, respectively. The high-resolution structures of Mycobacterium tuberculosis OppABCD in the
resting state, oligopeptide-bound pre-translocation state, AMPPNP-bound
pre-catalytic intermediate state and ATP-bound catalytic intermediate
state has been obtained. The structures show an assembly of a cluster C SBP with its ABC
translocator and a functionally required [4Fe-4S] cluster-binding domain
in OppD (Yang et al. 2024).
|
| Accession Number: | R4M537 |
|---|
| Protein Name: | Periplasmic oligopeptide-binding lipoprotein oppA |
|---|
| Length: | 591 |
|---|
| Molecular Weight: | 63507.00 |
|---|
| Species: | Mycobacterium tuberculosis CAS/NITR204 [1310114] |
|---|
| Number of TMSs: | 1 |
|---|
| Substrate |
peptide |
|---|
1: MADRGQRRGC APGIASALRA SFQGKSRPWT QTRYWAFALL TPLVVAMVLT GCSASGTQLE
61: LAPTADRRAA VGTTSDINQQ DPATLQDGGN LRLSLTDFPP NFNILHIDGN NAEVAAMMKA
121: TLPRAFIIGP DGSTTVDTNY FTSIELTRTA PQVVTYTINP EAVWSDGTPI TWRDIASQIH
181: AISGADKAFE IASSSGAERV ASVTRGVDDR QAVVTFAKPY AEWRGMFAGN GMLLPASMTA
241: TPEAFNKGQL DGPGPSAGPF VVSALDRTAQ RIVLTRNPRW WGARPRLDSI TYLVLDDAAR
301: LPALQNNTID ATGVGTLDQL TIAARTKGIS IRRAPGPSWY HFTLNGAPGS ILADKALRLA
361: IAKGIDRYTI ARVAQYGLTS DPVPLNNHVF VAGQDGYQDN SGVVAYNPEQ AKRELDALGW
421: RRSGAFREKD GRQLVIRDLF YDAQSTRQFA QIAQHTLAQI GVKLELQAKS GSGFFSDYVN
481: VGAFDIAQFG WVGDAFPLSS LTQIYASDGE SNFGKIGSPQ IDAAIERTLA ELDPGKARAL
541: ANQVDELIWA EGFSLPLTQS PGTVAVRSML ANFGATGLAD LDYTAIGFMR R