1.A.1.11.20
The voltage-gated Ca2+ channel, L-type α-subunit, Eg1-19 regulated by Macoilin (8.A.38.1.2)
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| Accession Number: | A8PYS5 |
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| Protein Name: | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog |
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| Length: | 1879 |
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| Molecular Weight: | 214983.00 |
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| Species: | Brugia malayi (Filarial nematode worm) [6279] |
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| Number of TMSs: | 19 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
calcium(2+) |
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1: MASSTEEDDH HAEDPHKSDL WQQTLQAAVA ATSQSEAAKK RQQQRKPMRQ NNVVERSERS
61: LLCLTLSNPL RKACITIVEW RPFEWLILLM ICANCIALAV YQPYPAQDSD TKNIILEQIE
121: YLFIVVFTIE CVLKVIALGF LFHPGAYLRN AWNILDFIIV VIGLVSTALS RMNIQGFDVK
181: ALRAFRVLRP LRLVSGVPSL QVVLNAILRA MIPLLHIALL VMFVIIIYAI IGLELFCGKL
241: HSTCFDPTTG ELAQHTPSTC GFASSAFHCQ PNGHYEGVHW VCTSNTSWQG PNNGITNFDN
301: FGLAMLTVFQ CVSLEGWTDV MYWVNDAVGR EWPWIYFVTL VILGSFFVLN LVLGVLSGEF
361: SKEREKARAR GLFQKFREKQ QLEEDLKGYL DWINQAEDIE PVNDDEQEDE QQFNGEELDE
421: ETDEKTDDSR PSWWKKRLRR MQKLNRRCRR GCRRLVKSQT FYWLVIVLVL LNTLVLTTEH
481: YKQEPWLDHF QTVANLFFVI LFSMEMILKM YSLGLTTYTT SQFNRFDCFV VISSIVEFVL
541: VYFDLMKPLG VSVLRSARLL RIFKVTKYWT SLRNLVSSLL NSLRSIMSLL LLLFLFIVIF
601: ALLGMQVFGG KFNFNPMNPK PRANFDTFIQ ALLTVFQILT GEDWNTVMYN GIASFGGVGS
661: WGVLVSVYFI VLFICGNYIL LNVFLAIAVD NLADADSLTN AEKEEEQAEV EEEVAEDDYE
721: DEKYDENGNE ETRDDSRIVM EEEEEGGEII TARPRRMSEL VTAKQQKPIP KASSLFILSH
781: TNPFRVFCNK IVNHSYFTNS VLICILVSSA MLAAEDPLEA QSPRNTILNY FDYFFTTVFT
841: VEITLKVVVY GLMFHKGSFC RNAFNLLDIL VVAVSLVSFV LKSDAISVVK ILRVLRVLRP
901: LRAINRAKGL KHVVQCVIVA VKTIGNIMLV TFMLQFMFAI IGVQLFKGTF FRCTDESKMT
961: EYECRGEFLA YEDGDPMKPL RMRREWIKND FNFDNVGDAM ISLFVVSTFE GWPDLLYVAI
1021: NSNEEDHGPV YNARQAVAIF FITFIVVIAF FMMNIFVGFV IVTFQNEGER EYENCELDKN
1081: QRKCIEFALK AKPHRRYIPR NRFQYRVWWF VTSQFFEYVI FIIILLNTTT LAMKHYPPDP
1141: GMDHVLDVLN LIFTGVFALE AVFKIIALNP KNYFGDRWNA FDFVIVLGSF IDIIYGKLSP
1201: GSNIISINFF RLFRVMRLVK LLSRGEGIRT LLWTFMKSFQ ALPYVALLIV LLFFIYAVIG
1261: MQVFGKVALN DETHIHRNNN FHTFPAAVLV LFRSATGEAW QEIMLSCSDR DEVKCDPASD
1321: DYKQNPDAKC GVDFAYPYFI SFFMLCSFLV INLFVAVIMD NFDYLTRDWS ILGPHHLEEF
1381: VRLWSEYDPD AKGRIKHLDV VTLLRKISPP LGFGKLCPHR LACKRLVSMN MPLNSDGTVC
1441: FNATLFALVR TNLKIYTEGN IDEVNEQLRS AIRRIWKRTP QKMLDEVVPP AGRDDDVTVG
1501: KFYATFLIQD YFRRFKKRKE LESKGIVPQQ TSQAMALQAG LRTLHEIGPE LKRAISGNLE
1561: TDFTLDVEEP QHRRPHSLFN NIISALGGSA RANQIYREDR TTRSLSMTAN NQLSPTRSLY
1621: GNNDMVSVTA HGHLTSNCSI NIPPSARSNG GVLQRRLPQI PSPNISFNQK LLENDLLVSR
1681: LALNAESHYI LANRSMPLDT DEEEEWGERR DTNRLRNDET WMNNGRPGKG LRKPFMLARN
1741: QAMAIAGVPA DISEAFEGTY RPAPDGKSVR LPLSNRPVLR PDRNEEGLTG RLVGEALALG
1801: RYMDERVVEA ARREIAEAYS LEESELESAA ATLADARYME HLGMERCEVR DFNRYSARAL
1861: LRPAPSQEAP EDDLFITTL