1.A.10.1.24
Glutamate-gated receptor 3.6 of 903 aas, GLR3.6. It probably acts
as non-selective cation channel, transporting Ca2+ into the cell. It mediates leaf-to-leaf wound signaling. GLR3/6 may be involved in light-signal transduction and calcium homeostasis
via the regulation of calcium influx into cells (Mousavi et al. 2013). Together with GLR3.3 (TC# 1.A.10.1.10), it plays a roles in nervous system-like signaling in plant defense. GLR3.3 and GLR3.6 play different roles
by a mechanism that differs substantially from that in animals (Toyota et al. 2018). The orthologous channel protein in Dionaea muscipula may play a role in touch-induced hair calcium-electrical signals that excite the Venus flytrap (Scherzer et al. 2022).
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| Accession Number: | Q84W41 |
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| Protein Name: | Glutamate receptor 3.6 |
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| Length: | 903 |
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| Molecular Weight: | 100530.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 3 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
inorganic cation, calcium ion |
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1: MKWFLLMLII CNAVPLQGLT KIVSARPQVV NIGSVFTFNS LIGKVIKVAM DAAVEDVNAS
61: PSILNTTTLR IIMHDTKYNG FMSIMEPLQF MESETVAIIG PQRSTTARVV AHVATELKIP
121: ILSFSATDPT MSPLQFPFFI RTSQNDLFQM AAIADIVQFY GWREVVAIYG DDDYGRNGVA
181: ALGDRLSEKR CRISYKAALP PAPTRENITD LLIKVALSES RIIVVHASFI WGLELFNVAR
241: NLGMMSTGYV WIATNWLSTI IDTDSPLPLD TINNIQGVIT LRLHTPNSIM KQNFVQRWHN
301: LTHVGLSTYA LYAYDTVWLL AQAIDDFFKK GGNVSFSKNP IISELGGGNL HLDALKVFDG
361: GKIFLESILQ VDRIGLTGRM KFTSDRNLVN PAFDVLNVIG TGYTTIGYWF NHSGLSVMPA
421: DEMENTSFSG QKLHSVVWPG HSIKIPRGWV FSNNGRHLRI GVPNRYRFEE VVSVKSNGMI
481: TGFCVDVFIA AINLLPYAVP FELVAFGNGH DNPSNSELVR LITTGVYDAG VGDITIITER
541: TKMADFTQPY VESGLVVVAP VRKLGSSAMA FLRPFTPQMW LIAAASFLIV GAVIWCLEHK
601: HNDEFRGPPR RQVITTFWFS FSTLFFSHRE TTTSNLGRIV LIIWLFVVLI INSSYTASLT
661: SILTVHQLSS PIKGIETLQT NHDPIGYPQG SFVRDYLIHE LNIHVSRLVP LRSPEEYDKA
721: LRDGPGKGGV AAVVDERAYI ELFLSNRCEF GIVGQEFTKN GWGFAFPRNS PLAVDVSAAI
781: LQLSENGDMQ RIRDKWLLRK ACSLQGAEIE VDRLELKSFW GLFVVCGVAC VLALAVYTVL
841: MIRQFGQQCP EEAEGSIRRR SSPSARIHSF LSFVKEKEED AKARSSRERQ LEDISANGSS
901: RCN