1.A.23.4.20 Mechanosensitive ion channel protein, putative, of 1812 aas and 6 TMSs in a 4 (N-terminal) + 2 (central) TMS arrangement (Wunderlich, 2022).
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Accession Number: | Q8IIS3 |
Protein Name: | Mechanosensitive ion channel protein, putative |
Length: | 1812 |
Molecular Weight: | 213622.00 |
Species: | Plasmodium falciparum (isolate 3D7) [36329] |
Number of TMSs: | 6 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
ion |
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1: MNEEKDENLK PFSRSKYPQS LMIDMSRSYM TKQDRINALN LYIQKSSYNP QLLQDDEEED
61: DEGESETIGD IILRILSIIF PDVSPGLWFF IHFIMNLIVL CVSLSSLSEP NVHDPISEPK
121: YNRKFIYGSM YCSFLILGIN IASFSILMSL HAIVQKFILE KLLQPSALCA AFYNTVDPEL
181: VYLFWSSIQI IYWRTNIILK SDSNENNNNN YYILRIFGYK DDETPFMFLK NIHWLITFPI
241: LLYIVFAVRL LFLSIISFIF ELGFLMNAHD LLGKYLRKYG VLRKFNIEWF MFVADKQENI
301: RTLFGYELYQ DERIMKQIER DDISKKFIQN TAELLLFKNL PRNCTCCKIT INRNKKNTMK
361: LLLPPVFEAK NIIKSESSSL KNWLACHYVV NTPPLLFLLN NSIALTNKNS IRNASDIFFR
421: QIIMSLKIYY QEKNDTYAFT TTPIHNNNNN NNNNNNNNNN NISMDGLSPH SNILNINTNE
481: KNQFFLKHKK TFPSKTNPNK VIPQEKFKKK KKNFHTYDSS DDDRQKKINL ENIFHDVDTY
541: DTKDEGTKDE NLTDQDKTSH HMIYEQNIQK IQSIKLSENI NKNKKRDTSK NKSKQTSKTK
601: KKKNIPGEHM NHMGKMSQTK KENDKNVEEQ NEQKKKKKDK MDNLKVKNQM IHIEKENYNV
661: NNVKIINNDI TNEISDTTMN IIKQDQINEK QNYDIITKTK ENLMNNSDKG NIDILPNEKY
721: NVDKHIHNIN VDKDIKDGCH FYDMTNSNMN DTKFNILITP SFSTIQNKKD INDTCEKDYT
781: SNKMNKIKNN DDNNDNNNDN NNDDDNNNII ICEDEINHEL KYNIKGGDKE EYSNQLENYN
841: SIAVQINDFN IDDVLKKKYT NESIHKMEKN SFEDNDIMIP KNNEILQNGN NEIWHNNNNI
901: KKEDAYDDYL EDKDNKKDNF HFNEIPLLGG FLFKRNEESV DGNISNMNKN SCNEEDMNNN
961: ENIEYHIPFY KKKKEKSGRK LKSSGKEKHT YEINKGNKNI KNRWSLNKNT YYYHSHLLNE
1021: EMNILERSDA INVKRYREEH NKDRYKVCKK MFRCLFCKRY KKEERLDKIR KDISSDLEDP
1081: FVMNVKSPIQ LTLSGNEYIT KDMIEVFLKP EETEEFMKEF DLSGHGKIDI IMFRNAIKRA
1141: ISCRKKFIKS LKGQESILKL VRRLMSILLS FLASVVLLFL FGVSADTIIV TGAAFITAVT
1201: VILSYMYTNF ITSVIFIAFS NPYNIGDRIR LDGGEAMYIK KIKTYTTEFE TTTGKIVIYE
1261: NSKLSNVKIY NESRSKNAYI DISFKVDINT PLVALKELRK SLQCLVDSRP SDFCKTKNLY
1321: FGYSLQPGHF YEISFWIKCV EGWGNWRKVF ELRTDIYDFI ILQLRILSIS YRLPTQKIGF
1381: TAPLNIADGY NNNNNNNNNN NNNIQSNYNI NRNINNNMNI NTQQPKINYP PHGNNNFPTH
1441: HLRYNRNKPL QYTSPPKEAR NPLFLETAKH KREFDISSIQ SNNEQHEAPN HIIYNEPVNF
1501: EDQPLKKNKL RSVYNSYKYV ESTNHNNMDT SIENGNGYMY ESYLQKNEDN NDYFVYNKKK
1561: KKNNKKKKTH DFNTKKNINI NNNNNNNNKM NNNKNNLFMN TFQNNVQSIS SMNNYHDVYY
1621: NNDKYYKTLH GQQNLYNNNN IKNINNHENI DNHNYNKINN ILYNYTNTNL ITSDNSYSYD
1681: NKKIIKCNYV PDVSNSDDSN HTDNMKGNNI YRNNNNFNNN SNNMKVKRGD HFNPIYPYND
1741: DIYTAHKNKE PQNIFENLYK LKKISNTNLD EKNYFSYDSS SGYDSYDCVK HFTYLHDKKQ
1801: NILLKRRKIK MA