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1.A.24.1.17 Gap Junction protein GJD3 (GJA11; GJC1) of 294 aas and 4 TMSs. A rare haplotype of the GJD3 gene segregating in familial Meniere's disease interferes with connexin assembly (Escalera-Balsera et al. 2025).
Accession Number:	Q8N144
Protein Name:	Gap junction delta-3 protein
Length:	294
Molecular Weight:	31933.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	4
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	ion

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MGEWAFLGSL LDAVQLQSPL VGRLWLVVML IFRILVLATV GGAVFEDEQE EFVCNTLQPG 
61:	CRQTCYDRAF PVSHYRFWLF HILLLSAPPV LFVVYSMHRA GKEAGGAEAA AQCAPGLPEA 
121:	QCAPCALRAR RARRCYLLSV ALRLLAELTF LGGQALLYGF RVAPHFACAG PPCPHTVDCF 
181:	VSRPTEKTVF VLFYFAVGLL SALLSVAELG HLLWKGRPRA GERDNRCNRA HEEAQKLLPP 
241:	PPPPPPPPAL PSRRPGPEPC APPAYAHPAP ASLRECGSGR GKASPATGRR DLAI

1.A.24.1.17
Gap Junction protein GJD3 (GJA11; GJC1) of 294 aas and 4 TMSs. A rare haplotype of the GJD3 gene segregating in familial Meniere's disease interferes with connexin assembly (Escalera-Balsera et al. 2025).

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1.A.24.1.17Gap Junction protein GJD3 (GJA11; GJC1) of 294 aas and 4 TMSs. A rare haplotype of the GJD3 gene segregating in familial Meniere's disease interferes with connexin assembly (Escalera-Balsera et al. 2025).

Cross database links:

External Searches:

Analyze:

1.A.24.1.17
Gap Junction protein GJD3 (GJA11; GJC1) of 294 aas and 4 TMSs. A rare haplotype of the GJD3 gene segregating in familial Meniere's disease interferes with connexin assembly (Escalera-Balsera et al. 2025).