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1.A.25.1.14
Innexin 2, Inx2; Prp33, of 367 aas and 4 TMSs. It is a structural components of gap junctions, and is involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis (Bohrmann and Zimmermann 2008). In embryonic epidermis, it is required for epithelial morphogenesis as well as for keyhole formation during early stages of proventriculus development in response to wg signaling (Bauer et al. 2004). In follicle cells, it promotes the formation of egg chambers, in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, it is required for survival of early germ cells and for cyst formation (Mukai et al. 2011).   

Accession Number:Q9V427
Protein Name:Innexin inx2
Length:367
Molecular Weight:42488.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

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FASTA formatted sequence
1:	MFDVFGSVKG LLKIDQVCID NNVFRMHYKA TVIILIAFSL LVTSRQYIGD PIDCIVDEIP 
61:	LGVMDTYCWI YSTFTVPERL TGITGRDVVQ PGVGSHVEGE DEVKYHKYYQ WVCFVLFFQA 
121:	ILFYVPRYLW KSWEGGRLKM LVMDLNSPIV NDECKNDRKK ILVDYFIGNL NRHNFYAFRF 
181:	FVCEALNFVN VIGQIYFVDF FLDGEFSTYG SDVLKFTELE PDERIDPMAR VFPKVTKCTF 
241:	HKYGPSGSVQ THDGLCVLPL NIVNEKIYVF LWFWFIILSI MSGISLIYRI AVVAGPKLRH 
301:	LLLRARSRLA ESEEVELVAN KCNIGDWFLL YQLGKNIDPL IYKEVISDLS REMSGDEHSA 
361:	HKRPFDA