1.A.25.1.14
Innexin 2, Inx2; Prp33, of 367 aas and 4 TMSs. It is a structural components of gap junctions, and is involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis (Bohrmann and Zimmermann 2008). In embryonic epidermis, it is required for epithelial morphogenesis as well as for keyhole formation during early stages of proventriculus development in response to wg signaling (Bauer et al. 2004). In follicle cells, it promotes the formation of egg chambers, in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, it is required for survival of early germ cells and for cyst formation (Mukai et al. 2011).