1.A.3.1.6 Ryanodine-sensitive calcium release channel receptor, RyR of 5071 aas and 6 putative TMSs. The tissue lecalization has been described (Hamada et al. 2002). Required for neuronal regeneration (Sun et al. 2014).
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Accession Number: | P91905 |
Protein Name: | Ryanodine receptor |
Length: | 5071 |
Molecular Weight: | 576362.00 |
Species: | Caenorhabditis elegans [6239] |
Number of TMSs: | 6 |
Substrate |
calcium(2+) |
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1: MADKEEQGGG EQDDVSFLRT GDIVCLSCVA SHNRDGVLGS ERVCLCTEGF GNRMCTLENV
61: SDKDIPPDIA MCMLYIDNAL SMRALQEMMS ADSDHKSASG AGGHKTLLYG HAVQLKHVQS
121: EMYLACLSSC SSNDKLAFDV GVQETNEGEA CWWTIHPASK QRSEGEKVRV GDDVILVSVA
181: TERYLHMAYS KGYMVIASFH QTLWNIQSVS SGSMRTRNMG FLFGNDVLRL FHGNDECLTI
241: PENWSEHPQH NMVIYEGGAA VTQARSLWRV ELIRMKWHGA LVGWEQVFRI KHITSGRYLG
301: VLDNSVQLYH KEKADFDLTA FVMCQNKDPK KQMLDEKEEE GMGNATIRYG ETNAFIQHVK
361: TQLWLSYQTT EVTKKGLGKV EEKKAVALKD GHMDDCYTFF MALEEESKSA RVIRKCSSVL
421: NKFLKGIDAL QLEGNQSTDW TRVDLNEVLK LMEDLIEYFA QPNDEQDFEE KQNHLRALRS
481: RQDLFQEEGV LNMILDTIDK FSQMEALPDF AGLIGEETHV KWEQISTYLY LLVAAMIKGN
541: HYNCAQFASA QRLDWLFGRL SNPQSAEGIL DVLYCVLTES PEALNMINEG HIRSVISLLE
601: KVGRDPKVLD VLSSLCEGNG MAVRSSQNLI TQYLLPGKDL LLQTSMRDHV SSMMPNVMLG
661: VVEGSALFRK WYFEAEVEHI ETMTKQTPYL RIGWANSVGF KPFPGSGDKM GCNGVGDDFY
721: SYGFDGKSMY FGGKSRRVGH KLLEKGDVIG CSIDLTIPEI KFSVNGTYMS GSFKKFNIDG
781: YFFPVMSLSA KVSCRFILGG NQGRLRYGPP TGFSAVVEAV NGELQITDCL SFGDLGKNIF
841: SGPQTIFNNL EPFIPTPIDV SATQLNHHAT EMHQKYAENL HELWAMRKIE LGWSYGETRS
901: ETSRKHPCLT KFEYLPETEK KYNILLALTT MKTIEALGYH LITEDPPCRL RAVRLGPNFQ
961: QQNGYKPGPL DTHEIQLPAE LQPLTEALAR NTHNIWAKEK IKRGWTFGLS EHVDATQKRS
1021: PHLVPYEQVD ERIKQANRES AAENIRALQL FGIFLEPPAH EHDEVAEKEL RARKDNTRTY
1081: RAEATYAVCG GKWYFEFEIL TAGYMKIGWM DIGSTPEIQL GADDRSYAFD GYLGRKWHQG
1141: AETYGKEWKI GDVVGCFLDL NDRTISFSLN GELLLDPSGS EMAFDNVVCG DGLVPAMTLG
1201: SGQRGRLNFG QQSNSLKFFT TCGLQEGYEP FCVNMYRTMP MWFAKHFPRF EDISTLKSGS
1261: ILEVSRIPAT GNSPPCLKIL QKVTISEGGP SEKAKMEYIK LSLPVKCNDT FVKNKDKETI
1321: RRQLQEYKPR SQSVVSQIRA PGIPKEFDDN KEKKGFLRSM LGSKDSHESD DDRRSRTNSK
1381: QPSVDGDEPP AVRRSLLELP HDERQIAEDS MRDLNDRHSE KPKKGGLLSR LRDSSNTRKN
1441: FRDSDRRKEE KAAQLRQMKA NSRSFDAGSL DTSTLPTGQK DVLASSEMPL SGPGRQLTIK
1501: RSSIKKNKKG KKAEIALEKM EREKKGSIIP MDAQLDVLQE GDAHALVHHK DKVDEYYYGI
1561: RIFPGQDPSQ VWVGWVTTQY HYYNVNFDGS QGVRKCRFSE ADHHGTTVDS VQSQNCYMVN
1621: VSELLATTPD VANTKVSGTL IGCIIDTSIG ELSFQVGSTD TGIKFKLEPG AMLFPAAFVT
1681: PTATEILQFE LGRIKYTFPL SAAMFKSCEK SLVPFCPPRL TVEQIESVYW ARVPNETLRT
1741: TALKLSEVRG WSVLCNDPVR IMSVYIPEKD QSLDILEMIE MPDMLEFHRQ TLNLYCKLAS
1801: HGNHKVAHTL CQHIDEDQIM YAIKSHYLSG PMRQGFHDLL IGLHLMSHTA ARNSMAKEYV
1861: IPLVPQLQIK NVLDPDSESR YPQITGESVS MLSQMASEPV KKHVSREDEM KLLPPSVDFE
1921: ALKKHVMESL QSATHHAVMN CRDLIGGDNT NHFEPLFKLF DQLLVIGLIN DEELECLLRL
1981: IHPQAFDENY ETGTTQKGLT QLELAEPVKI QLVSILDHLC DIQLRYRIES LVAFTEGFVG
2041: ELQSDQCKRY MEIKQTDMPP AEAAKKTKEF RCPPKEQMFR LLMCKVKEER DPELMEEDAD
2101: VDQCPMAEGL QQQLRDFCEL LVGKIGNVKE GDSDDQLALI ESEEGSWVDS FARIVVKVPP
2161: PVLEEGMEMQ KKGTQNFREI IVTMLREWAQ ADFIESKSLI RNMFRLLLRQ YSGIREIRDA
2221: MSQTYVFHER NEKDVTDFLV YLIQIRELLT VQFEHTEEAI LKRGLWKLMN NRIFFQHPDL
2281: MRLLSVHENV MSIMMNILTA QQGTVEHEGD ELKEKAPIKD ASEMVVACSR FLCYFCRTSR
2341: QNQKAMFEHL SFLLDNATML LARPSLRGSV PLDVAYSSFM DNNELALALK EEELDKVAVY
2401: LSRCGLQPNS ELITKGYPDI GWDPVEGERY IDFLRFCVWI NGENVEENAN LVIRLLIRRP
2461: ECLGVALKGE GQGLFSAFKE AIALSEDIRL LENDSHPSLL SSGLLGENPT YPSKDAEGED
2521: YIDLGAATLD FYSSLVDLLA KCAPDPMAIQ AGKGDSLRAR AILRSLISLD DLGQILALRF
2581: TIPNLAAPSI EDTGPLPGLL PNHKGSVLLF LDRVYGIDQQ DMLFHVLEQS FLPDLRAATM
2641: MDSPRALESD TALALNRYLC NSVLPLLTNH SHFFADAEHH SALLDATLHT VYRMNRLKSL
2701: TKNQRDAVSD FLVAITRELP PAMMIKLLKK VITDILTMND MNVLVPLRLI TLHYERCGKY
2761: YGSGNHYGVA SEQEKRLSML LFDAIFDTLG SRPYDPELFG KALPCMTAIG SAISPDYTLT
2821: SGLEDVRNKR REEEGAWIPR TVDVSRCEIN RDLEKMTELF AEHFHDSWAS RKLEKGWVHG
2881: DLYSRANFTH PRLKPFALLK DFEKSFYKER CSECLKALMA WNYSFEMMDR DANDRASAAR
2941: TLSGTSISNF APKPIDLSSM TLEKDMVNAA EKMAEHSHLI WAKKVMNDLN TKGGFMPIPL
3001: VPWDLLTDFE RRKDRFRASE ILKFLQYHGY HVNCPKDEQS QNDRLKSEGE RTSVEKRFAY
3061: NLLEKLITYL EQASLKMKSV KPSQELTRRN SFKKEGQDVK FFEKVVLPLM HAYFNAHKNY
3121: FLEGSSIVQT GTASNKEKEM VANLFCRLAA LLRIKNRAFG SVAKITVKCL QGLTQALDLR
3181: TLVKVNSDIV RTSLLTFFNN CADDLYASVN ELKDGGQYSL IRGQALKSWN SFEFANQMIV
3241: PVLTTMFAHL ARNHFGTDLL LDDIQAACYK ILDSLYMVTG LSSSISHRKS ISGESEKHRP
3301: GLGQCLAAFA SCFPVAFLEP EFNKSNKFSV LAKSQDQSVQ VQEMLQNLST HIPHLEKLLT
3361: DLETVANNNT MYSDVPNVYD VDLPLMCSYM AHWFSVGPDG KRDKEDQRAS VVQTTSVSCD
3421: HINRIFNALL KMIRNHVGIE NAPWLCRVNF FAVQIIQNVT SDPVREFVLP IAERLRRMSE
3481: KAYKEEEHMR THPDDADEGT VAEDNARLVR DTYAFFPILM KYTDLHRAQW LKTPTWETDG
3541: VYENVAVIFR IWSQSQHFKR EELNYVAQFE EDAAATGGGD MKTGKAAIAE RKKKRREGQI
3601: KKDKHAASIV IACLKRLLPV GLNVFGGREL DIVQQSKEKF IQKETEEKIR EFIKGLLEIP
3661: VKTDPTDKNA WQLSLYRKIG KSQMRGKDEM SQDAVIEKIF NMGQVSAILH TMTSRMEKED
3721: IWKKVLTLQR KRMAISLITA SHLYKTELHR GINFFLPAFS RLWMEEEDAG QDQLIADICS
3781: GVEEEEGPRI EIIMEEGVPI VASSEDTKEK ETNPDPLKQL IRCFQRAATS EETAASAIHE
3841: DSLYIRFADV MAKSIHIEEE DGEDGEEGEI DQAAKEEQSQ ALRGEQAVLA SRGAAIMCLM
3901: YLSASGGEPN EMVAQTLQLG IHLLSGGNVE IQKMLIEYLQ LKKDVRFFTS MAGLMNKCSV
3961: LNLEMFERQI KAEGLGMGAE LASGDNQNLN DADFTCSLFR FLQLTCEGHN LEFQNYLRTQ
4021: PGHTTSVNLI NCTVDYLLRL QESVMDFYWH YSSKEVIDEG GKEYFLRAIQ VCSQVFNTLT
4081: ESIQGPCVGN QMTLANSRLW DAINGFFFLF AHMMEKLYKN STQLELLREF LNLQKDMIVL
4141: MLSMLEGNVL NGSIGKQMVD ALVESQPSVE KILKFSDMFL KLKDLTTSQA FQDFDTNQDG
4201: WISPKEFQRA MESQKMYTVE DITYLMMCTD VNNDGKVDYM EFTERFHNPA RDIGFNLAVL
4261: LVNLKEHITN DPRLEKIIEK AQTLLEYFDP FLGRIEIMGS SKRVEKIYFE IQESWLEQWG
4321: KQQIRDSKNS FLFNVLQDDG GDQGKLEAFI NFCEDTIFEM QHAAAISSGD SDTKMERAIK
4381: QRDYFLQQTS ADHISETFKS GYNYGISAAS ALSPQNISTT MRNVSSSVRQ MSWTQLLYAV
4441: IILFIRAGLA IGWAGYLLLM TIFRFGYFLT TSSEEEEAAR QEKEQAKMNN EHPSFNPPII
4501: QEFHHSHVGV TAFGVGMNAD HLNVNSLPDF VPPERPETPE TVLEEEKPLN QETSPPTSPT
4561: SPASKAPSIY ESIGAPQMVQ LQSEADFQQG QYEPKIAESN STKSRGSILN MLARNFKTIE
4621: KITLYLAFFI NVILLFHRVD ISHAENAEAA SEGDDDEDAL ESIFITGMQF PYVEYEITGW
4681: MLAQILYWIS VLHLSTSFAL LVSFYQLKIP LITFKREKEI ARKLMFDGCW ITEEDSEELG
4741: IVDTFMWYLD RIVVSAKSFP MMYWDKFVRR KTRSKFKDQV DEETLTSILG EEKMSTDSSY
4801: DYRYSCWLWI GVILTNGQFL YRVGYLLCSA CGVFLSPFFY AFHLIDVVLS FPMLKAILQS
4861: VTHNLQQLIL TIMMTLVVVY LYTVIAFNFF RKFYVQEGEE GEEPDRKCHN MLTCFIYHFY
4921: AGVRAGGGIG DELESPYGDD LEYPRMFYDI SFFFFVIIIL LAIMQGLIID AFGELRDQQE
4981: SATEKLESSC FICDIGKETF DRMPRGFEIH TTKEHNFANY LFFLQHLVNK DETEYTGQET
5041: YVREKYDNRD WDFFPVGECF VKQYEDQLLQ S