1.A.4.1.11
TRP channel homologue, Trp1, of 766 aas and 6 - 9 TMSs. Contains Ankyrin - PKD1 - TrpC channel domains. Exhibits properties of mammalian signal transduction Trp channels (Arias-Darraz et al. 2015). Photoswitchable reagents are used for
investigating various types of TRPC channels, including TRPC2, TRPC3,
TRPC5, and TRPC6, to gain new insights into the gating
mechanisms and functions of these channels (Ojha et al. 2023).
|
| Accession Number: | A8I051 |
|---|
| Protein Name: | Transient receptor potential ion channel protein |
|---|
| Length: | 766 |
|---|
| Molecular Weight: | 84280.00 |
|---|
| Species: | Chlamydomonas reinhardtii [3055] |
|---|
| Number of TMSs: | 9 |
|---|
| Substrate |
calcium(2+) |
|---|
1: MKVAPAPASG QPGGGSKKPS DYGCQLHYKH ARVVEPESTT DDGMKRLKDV GDKGTLITAA
61: ELGLVDKYRD LKRAGQDILT CDWPYHYSSI LYACYGNQYK ILQMVEREFV GSTQELTAMH
121: TTRCWVGKNS AMVAAYQGHL ETMLYIIDLD MQGKFTEDLF KQRDMMWAAS QGHTDTIEVL
181: LATSRGLRRP ASSQDALEAG VKHSDLVGKS AASTTAAAAA GGKTASGKPG EPGGGGAVKL
241: KDVHITVRTL QGVIVSAYRA GMNCMGVIMY CQSLLQQARY FDDLVAQLTA WEVKLLDTCR
301: NKQEVQAILA PTEDDPSEPV GYALATFDKA FLSHKFVQQI FTEKWDTMGV TDYTKSLFGV
361: VWGGCSLVVA FAAWATICPL VVVARSFLSP VQDFMMRGKV IVDSRFPWHV PLYRWLLTQC
421: ALITFTVLLS YLVFSFDPSD PVPASVAPLN TFLAVWCAAI LEYVEEGRAE YMSSGWNVMD
481: VTMALSYILH YILRIIAVRV TDNLNILLVV NDLLAAAALM AWFRMVSVFE LSSAIGPLIQ
541: MMKQALFQEA CIERDPTTNE CTKYTSWGYD WQKDGLVGGM TFLQYIALGN ANPVDFEQKR
601: VTGVIFYLIF AIVTAILLLN LFIAMLADTY TRVSTQAMVE FRYRKAKLMA SYSRRDFVCP
661: PFNLLHLVCA AVGNGLRRLV WGPDGFTPGE EMRQVVVLQR RVVDDFLNSN RVALFREKLN
721: AELPNLVHEM LKQKGKGDGG ALAGGGAAAS TTVLATAVSV TAAAGH