1.A.4.1.15
Transient potential protein-gamma, Trpγ, of 1128 aas and 10 TMSs. A light-sensitive cation/calcium channel that is required for inositide-mediated Ca2+ entry in the retina during phospholipase C (PLC)-mediated
phototransduction. It forms a regulated cation channel when
heteromultimerized with TrpL (Xu et al. 2000).
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| Accession Number: | Q9VJJ7 |
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| Protein Name: | Transient receptor potential-gamma protein |
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| Length: | 1128 |
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| Molecular Weight: | 127109.00 |
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| Species: | Drosophila melanogaster (Fruit fly) [7227] |
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| Number of TMSs: | 10 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
cation, calcium ion |
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1: MMEEENTIRP HQEIRQLTLE EKKFLLAVER GDMAGTRRML QKAQDTEYIN VNCVDPLGRT
61: ALLMAIDNEN LEMVELLINY NVDTKDALLH SISEEFVEAV EVLLDHENVT FHSEGNHSWE
121: SASEDTSTFT PDITPLILAA HRDNYEIIKI LLDRGAVLPM PHDVRCGCDE CVQSRQEDSL
181: RHSRSRINAY RALASPSLIA LSSKDPILTA FELSWELRRL SFLEHEFKNE YQELRKQCQD
241: FATALLDHTR TSHELEILLN HDPTGPVYEH GERMHLNRLK LAIKLRQKKF VAHSNVQQLL
301: ASIWYEGLPG FRRKNMALQA VDIIRIGIMF PIFSLAYILA PYSSIGQTMR KPFIKFICHS
361: ASYFTFLFLL MLASQRIETF IGGWFFADSS GMLNTMEELP TKRGAKPTFI EWLILAWVSG
421: LIWSEVKQLW DVGLQEYLND MWNVIDFVTN SLYVATVALR VVSFFQVQKE MIYNSHATDL
481: PRERWDAWDP MLISEGLFSA ANIFSSLKLV YIFSVNPHLG PLQVSLSRMV MDIMKFFFLY
541: VLVLFAFGSG LNQLLWYYAD LEKKRCPEVS PMSALLNMNG TNDPNACIVW RRFSNLFETT
601: QTLFWAVFGL IDLDSFELDG IKIFTRFWGM LMFGTYSVIN IVVLLNLLIA MMNHSYQLIS
661: ERADVEWKFA RSKLWISYFE EGGTCPPPFN IIPTPKSIWY AIKWMRRVFC SGSSAARREH
721: LKTIRRKAQQ ASDRDFKYQQ IMRNLVRRYV TVEQRKAESQ GVTEDDVNEI KQDISAFRCE
781: LVEILKNSGM DTNVTAGQGG GGGGKKNRQK ERRLMKGFNI APPGSTGSLA PVAEFSTSLD
841: NYDNQHEILS STLSTLFTPN FMHKRQQSQA GSGGGGSESP TTPTAPQGTQ GAAMTASSQV
901: TKYNKSALKP YNKRIAGHKK RWGTLIEAAK VGNVSKMLGR SKSEDSVCNS SHTSTPVHGQ
961: MRVTYAQNSP QQEYGYHGET SSTTISTPTP TISVVSNSPA AHAGVGSHFF HTTSGLTAIA
1021: ALKRKRKKFS SSKNICPVTE SVAAANAAEI LNDKTLKRVS SYPAAEAGVQ HNPAQLVKPR
1081: RHEQTQSQHD SVETNSTFTL SIDPSNTSVN SREPLISTSC VSTTGAIG