DWORF of 34 aas and 1 TMS (Nelson et al. 2016). Counteracts the inhibitory effects of single transmembrane peptides, phospholamban (TC# 1.A.50.1), sarcolipin (1.A.50.2) and myoregulin (1.A.50.3), on SERCA (TC# 3.A.3.2). Homology with the inhibitory peptides has not been established although all of these peptides have about the same size with a single C-terminal TMS.
|Protein Name:||Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF|
|Species:||Homo sapiens (Human)  |
|Number of TMSs:||1|
|Location1 / Topology2 / Orientation3:
Sarcoplasmic reticulum membrane1 / Single-pass membrane protein2
1: MAEKAGSTFS HLLVPILLLI GWIVGCIIMI YVVFS