1.A.64.4.5
Chemokine-like factor (CKLF)-like MARVEL transmembrane domain-containing protein 6, CMTM6, of 183 aas and 4 TMSs. It is recognized as one of its potential immunotherapy targets for treatment of endocrine cancer (Chen et al. 2024). CMTM6 mediates the Warburg effect and promotes the liver metastasis of colorectal cancer (Shaha et al. 2024).
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| Accession Number: | Q9NX76 |
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| Protein Name: | CKLF-like MARVEL transmembrane domain-containing protein 6 |
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| Length: | 183 |
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| Molecular Weight: | 20419.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MENGAVYSPT TEEDPGPARG PRSGLAAYFF MGRLPLLRRV LKGLQLLLSL LAFICEEVVS
61: QCTLCGGLYF FEFVSCSAFL LSLLILIVYC TPFYERVDTT KVKSSDFYIT LGTGCVFLLA
121: SIIFVSTHDR TSAEIAAIVF GFIASFMFLL DFITMLYEKR QESQLRKPEN TTRAEALTEP
181: LNA