1.B.1.1.11 Porin OmpPst1. Transports carbapenem antibiotics imipenem will slow flux and meropenem with rapid flux in a reconsituted ion conductance system (Bajaj et al. 2012).
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Accession Number: | J9VHK9 |
Protein Name: | Porin |
Length: | 371 |
Molecular Weight: | 41175.00 |
Species: | Providencia stuartii [588] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Cell outer membrane1 / Multi-pass membrane protein2 |
Substrate |
meropenem, 2-(Biaryl)carbapenems |
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1: MMKRNILAMV IPALLAAGAA NAAEVYNKDG NKLDVYGKVD VRHYFADADK KNDEKSEDGD
61: DSRVRLGVKG DTQITDQLTG FGRFEWETKT NKAEDNNENK NRLAYAGLKF ADFGSIDYGR
121: NYGVVYDTNA WTDVFPLWGA DTMAQSDNFM TSRNRNLLTY RNNNAFGYVD GLSFALQYQG
181: KNGDNNKSTA GVRKDNGDGF GFSTAYELGW GVTLGGGYSN SSRTPAQQKY DAAGGQKAQA
241: WNVGGKFDAN NVYLAAMYGQ TLNMTRYGDD GIANKTENVE LVAQYLFDFG LKPSIGYNQS
301: KGKDLGRTYN GKTYNNQDLV KYISVGSYYY FNKNMSAVVD YKINLLKDND FTRENGINTD
361: NVVGLGLVYQ F