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1.B.1.5.2 PorA porin, cation selective at pH > 6; anion selective at pH < 4 (a continuum electrodiffusion model accounts for the results) (Cervera et al., 2008). Both PorA and PorB have been used for vaccine development (Whiting et al. 2019).
Accession Number:	Q05520
Protein Name:	PorA
Length:	348
Molecular Weight:	37684.00
Species:	Neisseria meningitidis [487]
Location¹ / Topology² / Orientation³:	Cell outer membrane¹ / Multi-pass membrane protein²
Substrate	ion

Pfam:	PF00267
Gene Ontology GO:0009279 C:cell outer membrane GO:0005886 C:plasma membrane GO:0046930 C:pore complex GO:0005215 F:transporter activity GO:0006811 P:ion transport
References (3) [1] “Comparison of the class 1 outer membrane proteins of eight serological reference strains of Neisseria meningitidis.” Maiden M.C.et.al. 1904526 [2] “Topology of outer membrane porins in pathogenic Neisseria spp.” van der Ley P.et.al. 1652557 [3] “The porA gene in serogroup A meningococci: evolutionary stability and mechanism of genetic variation.” Suker J.et.al. 8057850

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

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FASTA formatted sequence

1:	EGRNIQLQLT EPLQNIQQPQ VTKRKSRIRT KISDFGSFIG FKGSEDLGEG LKAVWQLEQD 
61:	VSVAGGGATR WGNRESFVGL AGEFGTLRAG RVANQFDDAS KAIDPWDSNN VVASQLGIFK 
121:	RHDDMPVSVR YDSPEFSGFS GSVQFVPAQN SKSAYTPAHF VQQTPESQPT LVPAVVGKPG 
181:	SDVYYAGLNY KNGGFAGNYA FKYAKHANVG RDAFELFLLG SGSDEAKGTD PLKNHQVHRL 
241:	TGGYEEGGLN LALAAQLDLS ENADKTKNST TEIAATASYR FGNAVPRISY AHGFDFIERG 
301:	KKGENTSYDQ IIAGVDYDFS KRTSAIVSGA WLKRNTGIGN YTQINAAS

1.B.1.5.2
PorA porin, cation selective at pH > 6; anion selective at pH < 4 (a continuum electrodiffusion model accounts for the results) (Cervera et al., 2008). Both PorA and PorB have been used for vaccine development (Whiting et al. 2019).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

1.B.1.5.2PorA porin, cation selective at pH > 6; anion selective at pH < 4 (a continuum electrodiffusion model accounts for the results) (Cervera et al., 2008). Both PorA and PorB have been used for vaccine development (Whiting et al. 2019).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

1.B.1.5.2
PorA porin, cation selective at pH > 6; anion selective at pH < 4 (a continuum electrodiffusion model accounts for the results) (Cervera et al., 2008). Both PorA and PorB have been used for vaccine development (Whiting et al. 2019).