| |
|---|---|
| Accession Number: | Q03155 |
| Protein Name: | AidA aka AIDA-I |
| Length: | 1286 |
| Molecular Weight: | 132272.00 |
| Species: | Escherichia coli [562] |
| Number of TMSs: | 1 |
| Location1 / Topology2 / Orientation3: | Cell outer membrane1 / Multi-pass membrane protein2 |
| Substrate | |
Cross database links:
| Pfam: | PF03797 |
|---|---|
Gene Ontology
GO:0009279
C:cell outer membrane
GO:0009986
C:cell surface
GO:0005576
C:extracellular region
GO:0016021
C:integral to membrane
GO:0042597
C:periplasmic space
GO:0005886
C:plasma membrane
GO:0005515
F:protein binding
GO:0007155
P:cell adhesion
GO:0009405
P:pathogenesis
| |
References (5)[1] “AIDA-I, the adhesin involved in diffuse adherence of the diarrhoeagenic Escherichia coli strain 2787 (O126:H27), is synthesized via a precursor molecule.” Benz I.et.al. 1625582 [2] “Characterization and immuno-detection of AIDA-I adhesin isolated from porcine Escherichia coli.” Fang Y.et.al. 15950405 [3] “Processing of the AIDA-I precursor: removal of AIDAc and evidence for the outer membrane anchoring as a beta-barrel structure.” Suhr M.et.al. 8899706 [4] “Characterization of the essential transport function of the AIDA-I autotransporter and evidence supporting structural predictions.” Maurer J.et.al. 10559167 [5] “Novel roles for the AIDA adhesin from diarrheagenic Escherichia coli: cell aggregation and biofilm formation.” Sherlock O.et.al. 15547278
| |
| Structure: | |
External Searches:
|
Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
|
|||
1: MNKAYSIIWS HSRQAWIVAS ELARGHGFVL AKNTLLVLAV VSTIGNAFAV NISGTVSSGG 61: TVSSGETQIV YSGRGNSNAT VNSGGTQIVN NGGKTTATTV NSSGSQNVGT SGATISTIVN 121: SGGIQRVSSG GVASATNLSG GAQNIYNLGH ASNTVIFSGG NQTIFSGGIT DSTNISSGGQ 181: QRVSSGGVAS NTTINSSGAQ NILSEEGAIS THISSGGNQY ISAGANATET IVNSGGFQRV 241: NSGAVATGTV LSGGTQNVSS GGSAISTSVY NSGVQTVFAG ATVTDTTVNS GGNQNISSGG 301: IVSETTVNVS GTQNIYSGGS ALSANIKGSQ IVNSEGTAIN TLVSDGGYQH IRNGGIASGT 361: IVNQSGYVNI SSGGYAESTI INSGGTLRVL SDGYARGTIL NNSGRENVSN GGVSYNAMIN 421: TGGNQYIYSD GEATAAIVNT SGFQRINSGG TAPVQNSVVV TRTVSSAAKP FDAEVYSGGK 481: QTVYLWRGIW YSNFLTAVWS MFPGTASGAN VNLSGRLNAF AGNVVGTILN QEGRQYVYSG 541: ATATSTVGNN EGREYVLSGG ITDGTVLNSG GLQAVSSGGK ASATVINEGG AQFVYDGGQV 601: TGTNIKNGGT IRVDSGASAL NIALSSGGNL FTSTGATLPE LTTMAALSVS QNHASNIVLE 661: NGGLLRVTSG GTATDTTVNS AGRLRIDDGG TINGTTTINA DGIVAGTNIQ NDGNFILNLA 721: ENYDFETELS GSGVLVKDNT GIMTYAGTLT QAQGVNVKNG GIIFDSAVVN ADMAVNQNAY 781: INISDQATIN GSVNNNGSIV INNSIINGNI TNDADLSFGT AKLLSATVNG SLVNNKNIIL 841: NPTKESAGNT LTVSNYTGTP GSVISLGGVL EGDNSLTDRL VVKGNTSGQS DIVYVNEDGS 901: GGQTRDGINI ISVEGNSDAE FSLKNRVVAG AYDYTLQKGN ESGTDNKGWY LTSHLPTSDT 961: RQYRPENGSY ATNMALANSL FLMDLNERKQ FRAMSDNTQP ESASVWMKIT GGISSGKLND 1021: GQNKTTTNQF INQLGGDIYK FHAEQLGDFT LGIMGGYANA KGKTINYTSN KAARNTLDGY 1081: SVGVYGTWYQ NGENATGLFA ETWMQYNWFN ASVKGDGLEE EKYNLNGLTA SAGGGYNLNV 1141: HTWTSPEGIT GEFWLQPHLQ AVWMGVTPDT HQEDNGTVVQ GAGKNNIQTK AGIRASWKVK 1201: STLDKDTGRR FRPYIEANWI HNTHEFGVKM SDDSQLLSGS RNQGEIKTGI EGVITQNLSV 1261: NGGVAYQAGG HGSNAISGAL GIKYSF