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| Accession Number: | Q7BS42 |
| Protein Name: | Serine protease pic autotransporter |
| Length: | 1372 |
| Molecular Weight: | 146454.00 |
| Species: | Escherichia coli O44:H18 (strain 042 / EAEC) [216592] |
| Number of TMSs: | 1 |
| Location1 / Topology2 / Orientation3: | Cell outer membrane1 / Multi-pass membrane protein2 |
| Substrate | |
Cross database links:
| Pfam: | PF03797 PF02395 |
|---|---|
Gene Ontology
GO:0009279
C:cell outer membrane
GO:0009986
C:cell surface
GO:0005576
C:extracellular region
GO:0042597
C:periplasmic space
GO:0005886
C:plasma membrane
GO:0004252
F:serine-type endopeptidase activity
GO:0009405
P:pathogenesis
GO:0006508
P:proteolysis
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References (2)[1] “Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli.” Henderson I.R.et.al. 10531204 [2] “Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042.” Chaudhuri R.R.et.al. 20098708
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MNKVYSLKYC PVTGGLIAVS ELARRVIKKT CRRLTHILLA GIPAICLCYS QISQAGIVRS 61: DIAYQIYRDF AENKGLFVPG ANDIPVYDKD GKLVGRLGKA PMADFSSVSS NGVATLVSPQ 121: YIVSVKHNGG YRSVSFGNGK NTYSLVDRNN HPSIDFHAPR LNKLVTEVIP SAVTSEGTKA 181: NAYKYTERYT AFYRVGSGTQ YTKDKDGNLV KVAGGYAFKT GGTTGVPLIS DATIVSNPGQ 241: TYNPVNGPLP DYGAPGDSGS PLFAYDKQQK KWVIVAVLRA YAGINGATNW WNVIPTDYLN 301: QVMQDDFDAP VDFVSGLGPL NWTYDKTSGT GTLSQGSKNW TMHGQKDNDL NAGKNLVFSG 361: QNGAIILKDS VTQGAGYLEF KDSYTVSAES GKTWTGAGII TDKGTNVTWK VNGVAGDNLH 421: KLGEGTLTIN GTGVNPGGLK TGDGIVVLNQ QADTAGNIQA FSSVNLASGR PTVVLGDARQ 481: VNPDNISWGY RGGKLDLNGN AVTFTRLQAA DYGAVITNNA QQKSQLLLDL KAQDTNVSEP 541: TIGNISPFGG TGTPGNLYSM ILNSQTRFYI LKSASYGNTL WGNSLNDPAQ WEFVGMDKNK 601: AVQTVKDRIL AGRAKQPVIF HGQLTGNMDV AIPQVPGGRK VIFDGSVNLP EGTLSQDSGT 661: LIFQGHPVIH ASISGSAPVS LNQKDWENRQ FTMKTLSLKD ADFHLSRNAS LNSDIKSDNS 721: HITLGSDRAF VDKNDGTGNY VIPEEGTSVP DTVNDRSQYE GNITLNHNSA LDIGSRFTGG 781: IDAYDSAVSI TSPDVLLTAP GAFAGSSLTV HDGGHLTALN GLFSDGHIQA GKNGKITLSG 841: TPVKDTANQY APAVYLTDGY DLTGDNAALE ITRGAHASGD IHASAASTVT IGSDTPAELA 901: SAETAASAFA GSLLEGYNAA FNGAITGGRA DVSMHNALWT LGGDSAIHSL TVRNSRISSE 961: GDRTFRTLTV NKLDATGSDF VLRTDLKNAD KINVTEKATG SDNSLNVSFM NNPAQGQALN 1021: IPLVTAPAGT SAEMFKAGTR VTGFSRVTPT LHVDTSGGNT KWILDGFKAE ADKAAAAKAD 1081: SFMNAGYKNF MTEVNNLNKR MGDLRDTNGD AGAWARIMSG AGSADGGYSD NYTHVQVGFD 1141: KKHELDGVDL FTGVTMTYTD SSADSHAFSG KTKSVGGGLY ASALFESGAY IDLIGKYIHH 1201: DNDYTGNFAS LGTKHYNTHS WYAGAETGYR YHLTEDTFIE PQAELVYGAV SGKTFRWKDG 1261: DMDLSMKNRD FSPLVGRTGV ELGKTFSGKD WSVTARAGTS WQFDLLNNGE TVLRDASGEK 1321: RIKGEKDSRM LFNVGMNAQI KDNMRFGLEF EKSAFGKYNV DNAVNANFRY MF