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| Accession Number: | Q8FDW4 |
| Protein Name: | Serine protease sat autotransporter |
| Length: | 1295 |
| Molecular Weight: | 140043.00 |
| Species: | Escherichia coli O6 [217992] |
| Number of TMSs: | 1 |
| Location1 / Topology2 / Orientation3: | Cell outer membrane1 / Multi-pass membrane protein2 |
| Substrate | |
Cross database links:
| Entrez Gene ID: | 1039573 |
|---|---|
| Pfam: | PF03797 PF02395 |
| KEGG: | ecc:c3619 |
Gene Ontology
GO:0009279
C:cell outer membrane
GO:0009986
C:cell surface
GO:0005576
C:extracellular region
GO:0016021
C:integral to membrane
GO:0042597
C:periplasmic space
GO:0005886
C:plasma membrane
GO:0004252
F:serine-type endopeptidase activity
GO:0009405
P:pathogenesis
GO:0006508
P:proteolysis
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References (4)[1] “Identification of sat, an autotransporter toxin produced by uropathogenic Escherichia coli.” Guyer D.M.et.al. 11029690 [2] “Analysis of the genome structure of the nonpathogenic probiotic Escherichia coli strain Nissle 1917.” Grozdanov L.et.al. 15292145 [3] “Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.” Welch R.A.et.al. 12471157 [4] “Sat, the secreted autotransporter toxin of uropathogenic Escherichia coli, is a vacuolating cytotoxin for bladder and kidney epithelial cells.” Guyer D.M.et.al. 12117966
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MNKIYSLKYS AATGGLIAVS ELAKRVSGKT NRKLVATMLS LAVAGTVNAA NIDISNVWAR 61: DYLDLAQNKG IFQPGATDVT ITLKNGDKFS FHNLSIPDFS GAAASGAATA IGGSYSVTVA 121: HNKKNPQAAE TQVYAQSSYR VVDRRNSNDF EIQRLNKFVV ETVGATPAET NPTTYSDALE 181: RYGIVTSDGS KKIIGFRAGS GGTSFINGES KISTNSAYSH DLLSASLFEV TQWDSYGMMI 241: YKNDKTFRNL EIFGDSGSGA YLYDNKLEKW VLVGTTHGIA SVNGDQLTWI TKYNDKLVSE 301: LKDTYSHKIN LNGNNVTIKN TDITLHQNNA DTTGTQEKIT KDKDIVFTNG GDVLFKDNLD 361: FGSGGIIFDE GHEYNINGQG FTFKGAGIDI GKESIVNWNA LYSSDDVLHK IGPGTLNVQK 421: KQGANIKIGE GNVILNEEGT FNNIYLASGN GKVILNKDNS LGNDQYAGIF FTKRGGTLDL 481: NGHNQTFTRI AATDDGTTIT NSDTTKEAVL AINNEDSYIY HGNINGNIKL THNINSQDKK 541: TNAKLILDGS VNTKNDVEVS NASLTMQGHA TEHAIFRSSA NHCSLVFLCG TDWVTVLKET 601: ESSYNKKFNS DYKSNNQQTS FDQPDWKTGV FKFDTLHLNN ADFSISRNAN VEGNISANKS 661: AITIGDKNVY IDNLAGKNIT NNGFDFKQTI STNLSIGETK FTGGITAHNS QIAIGDQAVV 721: TLNGATFLDN TPISIDKGAK VIAQNSMFTT KGIDISGELT MMGIPEQNSK TVTPGLHYAA 781: DGFRLSGGNA NFIARNMASV TGNIYADDAA TITLGQPETE TPTISSAYQA WAETLLYGFD 841: TAYRGAITAP KATVSMNNAI WHLNSQSSIN RLETKDSMVR FTGDNGKFTT LTVNNLTIDD 901: SAFVLRANLA QADQLVVNKS LSGKNNLLLV DFIEKNGNSN GLNIDLVSAP KGTAVDVFKA 961: TTRSIGFSDV TPVIEQKNDT DKATWTLIGY KSVANADAAK KATLLMSGGY KAFLAEVNNL 1021: NKRMGDLRDI NGESGAWARI ISGTGSAGGG FSDNYTHVQV GADNKHELDG LDLFTGVTMT 1081: YTDSHAGSDA FSGETKSVGA GLYASAMFES GAYIDLIGKY VHHDNEYTAT FAGLGTRDYS 1141: SHSWYAGAEV GYRYHVTDSA WIEPQAELVY GAVSGKQFSW KDQGMNLTMK DKDFNPLIGR 1201: TGVDVGKSFS GKDWKVTARA GLGYQFDLFA NGETVLRDAS GEKRIKGEKD GRMLMNVGLN 1261: AEIRDNLRFG LEFEKSAFGK YNVDNAINAN FRYSF