TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.B.6.1.24
Omp38; OmpA of 356 aas and 1 N-terminal TMSs. It is a selective antibiotic transporting porin (Iyer et al. 2018; Jyothisri et al. 1999) and induces apoptosis in human cell lines through caspase-dependent and AIF-dependent pathways. Purified Omp38 enters host cells and localizes to the mitochondria, which presumably leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor) (Choi et al. 2005).

Accession Number:Q6RYW5
Protein Name:Outer membrane protein Omp38
Length:356
Molecular Weight:38420.00
Species:Acinetobacter baumannii [470]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate antimicrobial agent

Cross database links:

Structure:
3TD3   3TD4   3TD5   4G4Y   4G4Z   4G88     

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MKLSRIALAT MLVAAPLAAA NAGVTVTPLL LGYTFQDSQH NNGGKDGNLT NGPELQDDLF 
61:	VGAALGIELT PWLGFEAEYN QVKGDVDGAS AGAEYKQKQI NGNFYVTSDL ITKNYDSKIK 
121:	PYVLLGAGHY KYDFDGVNRG TRGTSEEGTL GNAGVGAFWR LNDALSLRTE ARATYNADEE 
181:	FWNYTALAGL NVVLGGHLKP AAPVVEVAPV EPTPVAPQPQ ELTEDLNMEL RVFFDTNKSN 
241:	IKDQYKPEIA KVAEKLSEYP NATARIEGHT DNTGPRKLNE RLSLARANSV KSALVNEYNV 
301:	DASRLSTQGF AWDQPIADNK TKEGRAMNRR VFATITGSRT VVVQPGQEAA APAAAQ