TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.B.94.1.1









Mycobacterial outer membrane porin PPE51 of 380 aas and about 8 TMSs. It is associated with the PE19 protein of 99 aas.  The complex probably transports a large range of nutrients and other solutes including propionamide, glucose and glycerol (Wang et al. 2020).

Bacteria
Actinomycetota
PPE51 of Mycobacterium tuberculosis
1.B.94.1.2









Mg2+-transporting outer membrane porin, PPE31 (399 aas)/PE20 complex (99 aas) (Wang et al. 2020).  The PPE31 protein probably has about 8 TMSs

Bacteria
Actinomycetota
Mg2+ porin, PPE31/PE20, of Mycobacterium tuberculosis
1.B.94.1.3









Heterodimeric outer membrane porin specific for inorganic phosphate, consisting of PPE25 of 365 aas and probably ~ 8 TMSs. The PE19 associated protein is of 99 aas (Wang et al. 2020).

Bacteria
Actinomycetota
PPE25/PE19 of Mycobacterium tuberculosis
1.B.94.1.4









Heterodimeric outer membrane porin consisting of two proteins, PPE65 of 413 aas and 8 probable TMSs, as well as PE32 of 99 aas. This porin transports inorganic phosphate (Wang et al. 2020).

Bacteria
Actinomycetota
PPE65/PE32 phosphate porin of Mycobacterium tuberculosis
1.B.94.1.5









Uncharacterized protein of 615 aas and ~ 12 TMSs, with applorimately 7 TMSs at the N-terminus in adomain that is similar to other members of the 1.B.94 family, and another domain of 5 TMSs at the C-terminus that resembles the proteins with TC# 8.A.128.2.4 and 3.

Bacteria
Actinomycetota
UP of Mycobacterium shinjukuense
1.B.94.1.6









PPE domain-containing protein of 626 aas and ~ 10 TMSs.

Bacteria
Actinomycetota
PPE protein of Mycobacterium tuberculosis
1.B.94.1.7









PPE20 of 539 aas and maybe as many as 8 TMSs/PE15 of 102 aas and maybe as many as 2 TMSs.  The Mycobacterium tuberculosis PE15/PPE20 complex transports calcium across the outer membrane (Boradia et al. 2022).

Bacteria
Actinomycetota
PPE20/PE15 of Mycobacterium canettii
1.B.94.1.8









Outer membrane porin PPE family protein, MT0318, of 3,186 aas and many (> 8) repeat units (Pajón et al. 2006).

Bacteria
Actinomycetota
MT0318 of Mycobacterium tuberculosis
1.B.94.1.9









The Proline-Proline-Glutamate (PPE) Family protein, PPE64, of 552 aas.  It is a heme-binding protein and forms pores in the outer membrane of Mycobacterium tuberculosis (Sankey et al. 2023). 

Bacteria
Bacillati, Actinomycetota
PPE64 of Mycobacterium tuberculosis