TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.C.103.1.1









The anion-selective, small, pore-forming, multistate, persister-promoting toxin, TisB (Gurnev et al., 2012; Steinbrecher et al., 2012). Forms a transmembrane amphipathic α-helix with all charged and hydrophilic residues on one side of the helix. TisB is activated in response to DNA damage by the SOS response and promotes persister formation in a manner similar to HokB (TC# 1.E.53.1.3; Harms et al. 2016).

Bacteria
Pseudomonadota
TisB of E. coli (A5A627)
1.C.103.1.2









Small toxic peptide, TisB 

Bacteria
Pseudomonadota
TisB of Klebsiella oxytoca (H3MU69)