TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.C.131.1.1









A secreted lipid binding protein of 1085 aas and 5 - 6 TMSs, VasX.  Essential for killing of Dictyostelium discoideum (Miyata et al. 2011).  It is a pore-forming toxin (Durand et al. 2014). It is a T6SS effector and may have a structure resembling that of Colicin Ia (Russell et al. 2014). VasW (295 aas, possibly with a C-terminal TMS) is an accessory protein for VasX (Miyata et al. 2013). The TsiV2 immunity protein (242 aas and 3 or 4 TMSs) protects against VasX. Its gene is adjacent to the vasX gene, and its promoter is within the vasX gene, clearly suggesting a common functional role to counteract the function of VasX (Miyata et al. 2013).

Bacteria
Pseudomonadota
VasX of Vibrio cholerae
1.C.131.1.2









Uncharacterized protein of 1174 aas and 6 putative TMSs.  May be a pore-forming toxin (Durand et al. 2014).

Bacteria
Pseudomonadota
UP of Pseudomonas aeruginosa
1.C.131.1.3









Uncharacterized protein of 955 aas.

Bacteria
Pseudomonadota
UP of Marinobacter manganoxydans
1.C.131.1.4









Uncharacterized protein of 1165 aas.

Bacteria
Pseudomonadota
UP of Vibrio coralliilyticus
1.C.131.1.5









Uncharacterized protein of 1142 aas

Bacteria
Pseudomonadota
UP of Pseudomonas syringae
1.C.131.2.1









Uncharacterized protein of 1007 aas and 6 putative TMSs.  May form pores in membranes (Durand et al. 2014).

Bacteria
Pseudomonadota
UP of Burkholderia thailandensis
1.C.131.2.2









Uncharacterized protein of 978 aas and 4 - 6 TMSs.  May be a pore-forming toxin (Durand et al. 2014).

Bacteria
Pseudomonadota
UP of Variovorax paradoxus
1.C.131.2.3









Uncharacterized protein of 947 aas.  This protein is 80% identical to a close homologue, shown to be a pore forming toxin, a T9SS effector, in Burkholderia thailandensis (Russell et al. 2014).

Bacteria
Pseudomonadota
UP of Burkholderia pseudomallei