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1.C.39.3.5 Complement protein C9; targets bacteria (McCormack et al. 2013). β-Hairpins in C8α and C9 play a direct role in MAC membrane penetration and pore formation (Weiland et al. 2014).
Accession Number:	P48770
Protein Name:	CO9 aka C9
Length:	547
Molecular Weight:	62014.00
Species:	Equus caballus (Horse) [9796]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Secreted¹ / Multi-pass membrane protein²
Substrate	small molecules, large molecules

RefSeq:	NP_001075419.1
Entrez Gene ID:	100034183
Pfam:	PF00057 PF01823
KEGG:	ecb:100034183
Gene Ontology GO:0005576 C:extracellular region GO:0005579 C:membrane attack complex GO:0006957 P:complement activation, alternative pathway GO:0006958 P:complement activation, classical pathway GO:0019835 P:cytolysis
References (1) [1] “Chimeric horse/human recombinant C9 proteins identify the amino acid sequence in horse C9 responsible for restriction of hemolysis.” Tomlinson S.et.al. 7541424

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FASTA formatted sequence

1:	MSAGRTFAFA ICILEVSVLT AGPTPNYAPE PEQQSGTPLP IDCRMSSWSE WSECDPCLRQ 
61:	MFRSRSIEVF GQFNGQRCVD AVGDRRQCVP TEACEEVEDD CGNDFQCGTG RCIKKRLLCN 
121:	GDNDCGDFSD EDDCENDPRP PCRERVVEES ELARTAGYGI NILGMDPLST PFDNEYYNGL 
181:	CDRVRDGNTL TYYRKPWNLA SLAYETKADK NFRIEHYEQQ IQAFRSVIEE RRSHFNADFT 
241:	LKFTPTEAKK CKQEPEESCN GTDSSENRIF RFAYSKNETY QLFLSYSSKK EKMFLHVKGV 
301:	IQLGKFVMRS RDVVLTTTFL DDIKALPTAY EKGEYIAFLE TYGTHYSSSG SLGGLYELIY 
361:	VLDKASMDQK GVELRDIQRC LGFNLDLSLK DKYEVTAKID KNDCLKRNEK EIVNIMDGSL 
421:	IDDVISLIRG GTRKYAFELK EKLLKGAKTV NVTDFVNWAS SLNDAPVLIS QRLSPIYNLI 
481:	PVKMKDAHQK KQNLERAIED YINEFSVRKC HPCQNGGTVI QIDGQCLCSC PIAFEGIACE 
541:	TGKKKIS

1.C.39.3.5
Complement protein C9; targets bacteria (McCormack et al. 2013). β-Hairpins in C8α and C9 play a direct role in MAC membrane penetration and pore formation (Weiland et al. 2014).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

1.C.39.3.5Complement protein C9; targets bacteria (McCormack et al. 2013). β-Hairpins in C8α and C9 play a direct role in MAC membrane penetration and pore formation (Weiland et al. 2014).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

1.C.39.3.5
Complement protein C9; targets bacteria (McCormack et al. 2013). β-Hairpins in C8α and C9 play a direct role in MAC membrane penetration and pore formation (Weiland et al. 2014).