1.R.1.1.3
Outer mitochondrial transmembrane helix translocase, MSP1, of 362 aas and 1 N-terminal TMS. It is required to remove mislocalized tail-anchored transmembrane proteins in mitochondria (Li et al. 2019; Matsumoto et al. 2019). Its structure indicates how this is accomplished (Sinning and McDowell 2022; McDowell et al. 2023McDowell et al. 2023).
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| Accession Number: | P28737 |
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| Protein Name: | Outer mitochondrial transmembrane helix translocase |
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| Length: | 362 |
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| Molecular Weight: | 40343.00 |
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| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
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| Location1 / Topology2 / Orientation3: |
Mitochondrion outer membrane1 / Single-pass membrane protein2 |
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| Substrate |
protein |
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1: MSRKFDLKTI TDLSVLVGTG ISLYYLVSRL LNDVESGPLS GKSRESKAKQ SLQWEKLVKR
61: SPALAEVTLD AYERTILSSI VTPDEINITF QDIGGLDPLI SDLHESVIYP LMMPEVYSNS
121: PLLQAPSGVL LYGPPGCGKT MLAKALAKES GANFISIRMS SIMDKWYGES NKIVDAMFSL
181: ANKLQPCIIF IDEIDSFLRE RSSTDHEVTA TLKAEFMTLW DGLLNNGRVM IIGATNRIND
241: IDDAFLRRLP KRFLVSLPGS DQRYKILSVL LKDTKLDEDE FDLQLIADNT KGFSGSDLKE
301: LCREAALDAA KEYIKQKRQL IDSGTIDVND TSSLKIRPLK TKDFTKKLRM DATSTLSSQP
361: LD