TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
2.A.133.1.1









Na+(Li+, K+)/H+ antiporter of 178 aas and 3 TMSs.  It's characterization was described by Shao et al. 2018 (see family description).

Bacteria
Bacillota
RDD family protein of Halobacillus andaensis
2.A.133.1.2









RDD family protein of 133 aas and 3 TMSs

Archaea
Euryarchaeota
RDD family protein of Methanosarcina barkeri (Q465I3)
2.A.133.1.3









Ser/Thr Kinase (N-terminus) linked to a RDD domain (C-terminus) of 3-4 TMSs (492 aas) 

Bacteria
Cyanobacteriota
S/T kinase/Rdd domain protein of Nodularia spumigena (A0ZK04)
2.A.133.1.4









Human 4TMS RDD protein fused N-terminally to a conserved hydrophilic domain of unknown function (413 aas)

Eukaryota
Metazoa, Chordata
RDD family protein of Homo sapiens (Q9UBU6)
2.A.133.1.5









YczC of 127 aas and 3 TMSs; RDD family

Bacteria
Bacillota
YczC of Bacillus subtilis
2.A.133.1.6









RDD family protein of 408 aas and 3 or 4 N-terminal TMSs

Bacteria
Bdellovibrionota
RDD protein of Bdellovibrio bacteriovorus
2.A.133.1.7









RDD family protein of 157 aas and 3 TMSs

Bacteria
Pseudomonadota
RDD protein of Vibrio cholerae
2.A.133.1.8









Uncharacterized RDD protein of 310 aas with 4 C-terminal TMSs.

Bacteria
Pseudomonadota
RDD protein of Stenotrophomonas maltophilia
2.A.133.1.9









RDD family/signal peptidase of 313 aas and 5 TMSs. The first 4 TMSs correspond to the RDD domain-containing family (TC# 2.A.133), while the 5th TMS plus the C-terminal hydrophilic domain corresponds to the signal peptidase domain, belonging to the CAAX peptidease superfamily (TC#s 9.B.1, 9.B.2, 9.B.391 and others (see the CAXX peptidase superfamily).

Bacteria
Candidatus Levybacteria
Peptidase of Candidatus Levybacteria bacterium
2.A.133.1.10









Uncharacterized protein of 240 aas and 3 TMSs.

Bacteria
Bacteroidota
UP of Nonlabens dokdonensis (Donghaeana dokdonensis)
2.A.133.1.11









Uncharacterized protein in the RDD or YckC Family of 151 aas and 3 N-terminal TMSs

Bacteria
Bacillota
YckC of Bacillus subtilis
2.A.133.1.12









RDD family protein of 179 aas and 3-4 TMSs

Bacteria
Bacillota
RDD family protein of Bacillus pumilus (B4AEM5)
2.A.133.1.13









RDD family protein of 159 aas and 3 TMSs.

Bacteria
Campylobacterota
RDD protein of Helicobacter pylori
2.A.133.2.1









RDD motif membrane protein 169 aas and 3 or 4 TMSs, required for growth with acetate as a sole carbon source (Deutschbauer et al. 2011).

Bacteria
Pseudomonadota
RDD protein of Shewanella oneidensi
2.A.133.2.2









Uncharacterized RDD motif-containing protein of 182 aas and 4 TMSs.

Bacteria
Pseudomonadota
UP of Collimonas fungivorans
2.A.133.2.3









Uncharacterized RDD family protein of 196 aas and 4 TMSs.

Bacteria
Pseudomonadota
UP of Morococcus cerebrosus
2.A.133.2.4









Uncharacterized RDD domain-containing protein of 157 aas and 3 TMSs

Bacteria
Actinomycetota
UP of Rhodococcus hoagii