2.A.18.6.9
Arginine-specific transporter, AAP3 (KM (Arg) = 2μM)
|
| Accession Number: | Q86G79 |
|---|
| Protein Name: | Arginine transporter AAP3 |
|---|
| Length: | 480 |
|---|
| Molecular Weight: | 52418.00 |
|---|
| Species: | Leishmania donovani [5661] |
|---|
| Number of TMSs: | 11 |
|---|
| Location1 / Topology2 / Orientation3: |
Vacuole membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
arginine |
|---|
| Pfam: |
PF01490
|
|---|
|
|
[1] “Novel motifs in amino acid permease genes from Leishmania.” Akerman M. et.al. 15522240
[2] “A novel high-affinity arginine transporter from the human parasitic protozoan Leishmania donovani.” Shaked-Mishan P. et.al. 16556218
|
1: MSKPSKSIPA QAEGEVLSDS LIDGNPGNAV DKHPSGEQGN HLHKNGSLTA SSSHNENGAD
61: AAKPGRNIIF RFTGWLIPYG GVISNCFSLG SVTLGGGIIS MPSSFAMSGI IMSVIYLVVI
121: TAATVYTMTL LGYAMKATGC KTFEELSLVL FGRGWDYFVG FVLWLSCFGT AVAYISAVSS
181: LITPILEKSP GTPAYLLTTS GNRLITSLIW LVFMVPVVIP KRVNSIRYVS AIGVFMVLYF
241: AVTIVVHSSM NGLKEGMRGD MKYFTSGNEA VYGLSIFIFS FLCQAVTGSV YFEQRPRPSV
301: RQLTIASAIS MTVCMVLYIF TGVFGYFDFA DDTQDSILYN FDPVHQPYMM IAYIGMLIKI
361: CAAFAMNMLP CRNFAYHCLN WDLETVPYWK HTIAILTMAV ATLVCGLFIP SINTAFGLVG
421: SLCGGFIGFI FPAYFWMYSG NWSLSSVGIW HWLATYFLVV AGVIAVVFGT ISTIYYSFFV