2.A.21.3.23
Kidney low affinity SGLT (Slc5a1) Na+:D-glucose symporter of 662 aas and 14 TMSs. Of the mammalian homologues, it most resembles SGLT2 (Althoff et al. 2006).
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| Accession Number: | Q2A679 |
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| Protein Name: | Solute carrier family 5 (Sodium/glucose cotransporter), member 1 |
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| Length: | 662 |
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| Molecular Weight: | 72891.00 |
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| Species: | Squalus acanthias (Spiny dogfish) [7797] |
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| Number of TMSs: | 14 |
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| Substrate |
sodium(1+), D-glucopyranose |
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1: MESSTVPAGS ATTPAGGSPG SSAVNNPADI SVIVIYFLVV LAVGIWAMVR TNRGTVGGFF
61: LAGRSMVWWP IGASLFASNI GSGHFVGLAG NGAAGGIATG GFEWNALVIV IILGWLFVPI
121: YIRAGVVTMP EYLKRRFGGN RIRIYLSVLS LCLYIFTKIS ADMFSGAIFI REALGLNLYV
181: AVVILLSITA LYTVTGGLAA VIYTDTLQTI IMVVGSFILM GFAFNEVGGY DAMKEKYMNA
241: ITSQTTDPIL NISAKCYTPR PDSFHLFRNP LTADLPWPGL IFGLSILAIW YWCTDQVIVQ
301: RCLSAKNMSH VKAGCILCGY LKLLPMYLMV FPGMVSRILY TDVVACVVPS LCKQYCDTEV
361: GCSNIAYPRL VVKLMPAGLR GLMLSVMLAS LMSSLTSIFN SASTLFTMDI WTKIRPKASE
421: KELMLAGRVF TLVLIGVSIA WIPIVQKAQS GQLFDYIQSI TSYLGPPIAA IFLLAIFVKR
481: VNEQGAFWGL IFGLAAGLSR MIAEFAFGTG SCVIPSNCPV IICGIHYLYF AIILFVATCL
541: MVLIVSLLTK PIDDIHLYRL CWTLRHSTEK REDLDSDDWN NQDNDSKMDV DEESPRDVKC
601: WKKAYNWFCG FEEQPQKLSK EEQEALQKQL TDISEVPLWR NVVNINAIIL LTVCVFFWAY
661: YA