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2.A.21.4.1 The monocarboxylate uptake (H⁺ symport?) permease, MctP (transports lactate (K_m = 4.4 μM), pyruvate (K_m = 3.8), propionate, butyrate (butanoic acid), α-hydroxybutyrate, L- and D-alanine (K_m = 0.5 mM), and possibly cysteine and histidine) (Hosie et al., 2002).
Accession Number:	Q8VM88
Protein Name:	MctP
Length:	491
Molecular Weight:	52258.00
Species:	Rhizobium leguminosarum (biovar viciae) [387]
Number of TMSs:	13
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	hydron, alanine, cysteine, histidine, lactate, 2-hydroxybutyrate, pyruvate, propionate, butyrate

Pfam:	PF00474
Gene Ontology GO:0016021 C:integral to membrane GO:0005215 F:transporter activity GO:0006814 P:sodium ion transport GO:0055085 P:transmembrane transport
References (1) [1] “A monocarboxylate permease of Rhizobium leguminosarum is the first member of a new subfamily of transporters.” Hosie A.H.et.al. 12218032

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MTTDINGTAL AVFIFFFVLV TVMGFVASRW RKPETLAHID EWGLGGRNFG TWITWFLVGG 
61:	DFYTAYTVIA VPALVYTVGA YGFFALPYTI VVYPFVFMVM PVLWKRAKDF GYVTAGDVVH 
121:	GQYGSRGLEL AVAATGVIAT MPYIALQLVG MTAVLKALGL HGELPLAIAF IVLALYTYSA 
181:	GLRAPALIAF VKDIMIYIVV IAAVALIPSK LGGYANVFAS ADAAFQAKGS GNLLLGGNQY 
241:	VAYATLALGS ALAAFMYPHT LTGIFASNSG KTIRKNAIML PAYTLLLGLL ALLGYMGHAA 
301:	NLKLDSANDV VPTLFKTLFS GWFFRFAFAA IAIGALVPAA VMSIGAANLF TRNFWKAYVD 
361:	PDVSDAGEAK VAKITSLVVK VGALLVIIFL PTQFALDLQL LGGIWILQTL PALVFGLYTN 
421:	WFRAPGLLAG WFVGFGGGTF LVWDAGWKPL HLISLGGEPF TVYTGLLALA ANIAVAVVVN 
481:	ALLPAKAPVR A

2.A.21.4.1
The monocarboxylate uptake (H⁺ symport?) permease, MctP (transports lactate (K_m = 4.4 μM), pyruvate (K_m = 3.8), propionate, butyrate (butanoic acid), α-hydroxybutyrate, L- and D-alanine (K_m = 0.5 mM), and possibly cysteine and histidine) (Hosie et al., 2002).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.21.4.1The monocarboxylate uptake (H+ symport?) permease, MctP (transports lactate (Km = 4.4 μM), pyruvate (Km = 3.8), propionate, butyrate (butanoic acid), α-hydroxybutyrate, L- and D-alanine (Km = 0.5 mM), and possibly cysteine and histidine) (Hosie et al., 2002).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.21.4.1
The monocarboxylate uptake (H⁺ symport?) permease, MctP (transports lactate (K_m = 4.4 μM), pyruvate (K_m = 3.8), propionate, butyrate (butanoic acid), α-hydroxybutyrate, L- and D-alanine (K_m = 0.5 mM), and possibly cysteine and histidine) (Hosie et al., 2002).