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2.A.31.2.7
Squid Na+-dependent Cl-/HCO3- symporter, NDCBE (1198 aas) (Piermarini et al., 2007b)

Accession Number:Q8I8G6
Protein Name:NDCBE
Length:1198
Molecular Weight:134259.00
Species:Loligo pealeii [6621]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Cl-, bicarbonate

Cross database links:

Pfam: PF07565    PF00955   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005452 F:inorganic anion exchanger activity
GO:0006820 P:anion transport

References (1)

[1] “Cloning of a Na+-driven Cl/HCO3 exchanger from squid giant fiber lobe.”  Virkki L.V.et.al.   12748067

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MAKSEQGSRM ETEAVRDLGS FVSSHTTSDA DIQDHRSQET VYIGLHVPRY RRHRKRHHRH 
61:	HRKDDVKEPF KTQNTDGTDA GISRAATPPS QRVQFLLGEG DEADEEHRPH DIFCEMAELH 
121:	YVDGEMEWKE SARWIKFEED VEEGGDRWSK PHVATLSLHS IFELRCAIMN GICMLDMDTA 
181:	NMQQVADLAL DNMVANKQLA EENRDKVRET LLSRHRHQHE KRHRKAEEGG SKLHLPIIRS 
241:	LADIGKKYSE PKNLSQNEEK TGTKSTPNLG LSRNNTSGGM SSISPTCSSL QPSPSFTNAD 
301:	LQEVPSSHKI NIHFMKKIPQ GAESANILVG EVEYLNHQVT GFIRLNKALI LGDLTEVPVP 
361:	TKFIFFLLGP LGNSNRYHEI GRSIATLMSD EVFHDVAYKA RNRDDLLAGI DEFLDQVTIL 
421:	PPGEWDPSIR IEPPKSVPSQ EGRKTPGSGA HLPNGKAMLE EEEDEHTDET LVRTGRIFGG 
481:	LITDIKRKAP FYLSDITDAL HVQSFASFVF LYFACLTPII TFGGLLGDAT EQNMAAFESI 
541:	LAGAICGIVY SLLAGQPLTI LGSTGPVLVF EKILYNFCSD YSLDYLCFRL WIGLWTGVIL 
601:	LIIVAFDLSA LVRYITRFTE ESFAALISLI FIVESLVKLF HILDDYPIKT SYSKELPTNC 
661:	SCLEPNITLV TPNATSINWD FVTKSNCTDL GGKLIGDGCK VHPYAADVFF LSFLLFCGTF 
721:	IIAMALKGIR NARFFPSVVR AIISDFAVII AIVSMVTLDA LVGVGTPKLL VPTEFKPTLS 
781:	TRSWVVNPFR NPWWTILAAV IPALLCTILI FMDQQITAVI VNRKENKLKK GHGYHLDLFI 
841:	VASLIMICSI LGLPWFVAAT VLSITHVMSL KKESQCTAPG ERPRFLGVRE QRVTGTMVFL 
901:	MIGISVMLTS ILMKIPMPVL YGVFLYMGVS SLRGMQLVCR VMILFMPAKY QPDYMYLRHV 
961:	RTTRVHLFTF IQLVCLGILW VIKTIKKISI AFPLMVLAMC FVRKAMDYIF TQRELKWLDD 
1021:	IMPEAHKRAK EDAEKQMQEE EMKLMEGVDP NIGSNVIGMP LEGMTISSEL DSVNITEEMT 
1081:	KTAIWKTIVA TDQSSIPQTD HPEKTHKSDR TENGKKKAKK HSKKTSPTKA TSDDSGLPPI 
1141:	PGSPRTEESG NNSDAVKSPK RRNLPVKFYI DESEEKEHLM TAPDIVVEPP SERGSPEK