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2.A.38.3.3 K⁺ or Na⁺ uptake uniporter or Na⁺-K⁺ uptake symporter, HKT1. (Banuelos et al, 2008). The high affinity HKT2;4 paralogue can function as a Ca²⁺-permeable cation channel (Lan et al., 2010).
Accession Number:	Q0D9S3
Protein Name:	HKT1
Length:	530
Molecular Weight:	59295.00
Species:	Oryza sativa (Rice Plant) [39947]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	sodium(1+), potassium(1+)

RefSeq:	NP_001058486.1
Entrez Gene ID:	4341971
Pfam:	PF02386
KEGG:	osa:4341971
Gene Ontology GO:0016021 C:integral to membrane GO:0015079 F:potassium ion transmembrane transporter act... GO:0006813 P:potassium ion transport GO:0006814 P:sodium ion transport GO:0055085 P:transmembrane transport
References (5) [1] “Two types of HKT transporters with different properties of Na+ and K+ transport in Oryza sativa.” Horie T.et.al. 11489190 [2] “Sodium transport and HKT transporters: the rice model.” Garciadeblas B.et.al. 12795699 [3] “The map-based sequence of the rice genome.” International rice genome sequencing project (IRGSP)et.al. 16100779 [4] “Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana.” The rice annotation project (RAP)et.al. 17210932 [5] “Glycine residues in potassium channel-like selectivity filters determine potassium selectivity in four-loop-per-subunit HKT transporters from plants.” Maeser P.et.al. 11959905

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MTSIYHDFIH NKLQSFGRIG RYFVNFVVLA HRFIALHIHP FWIQLSYFLL ISILGSVLLM 
61:	FLKPSNPEFR PGYIDMLFLS TSALTLSSLI TIEMEVLSSS QIVVITLLML LGGEVFVSFL 
121:	GLMLRLNHKH NPEFSGDKVS SVPIELDTIN SASTVISCEE LQLEAAIPEV PSSTIKDLKR 
181:	SKRLRWFLGF VVFSYFVVIH VAGFLLVLWY ISRVSSAKAP LKKKGINIAL FSFSVTVSSF 
241:	ANVGLVPTNE NMAIFSKNPG LLLLFIGQIL AGNTLYPLFL RLLIWFLGKV TKLRELKLMI 
301:	KNPEELQYDY LLPKLPTAFL ASTVIGLMAS LVTLFGAVDW NSSVFDGLSS YQKIINALFM 
361:	AVNARHSGEN SIDCSLIAPA VLVLFIILMY LPPSTTFALS NGDEKTANKK AKRKLGLVVQ 
421:	NLAFSQLACI SVFVIVAFIT ERSRLRNDPL NFSALNMIFE IISAYGNVGL STGYSCSRLQ 
481:	KLHPGSICQD KPYSLSGWWS DEGKLLLVFV MLYGRLKAFT KGTGEYWRLW

2.A.38.3.3
K⁺ or Na⁺ uptake uniporter or Na⁺-K⁺ uptake symporter, HKT1. (Banuelos et al, 2008). The high affinity HKT2;4 paralogue can function as a Ca²⁺-permeable cation channel (Lan et al., 2010).

Cross database links:

Gene Ontology

References (5)

External Searches:

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2.A.38.3.3K+ or Na+ uptake uniporter or Na+-K+ uptake symporter, HKT1. (Banuelos et al, 2008). The high affinity HKT2;4 paralogue can function as a Ca2+-permeable cation channel (Lan et al., 2010).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

2.A.38.3.3
K⁺ or Na⁺ uptake uniporter or Na⁺-K⁺ uptake symporter, HKT1. (Banuelos et al, 2008). The high affinity HKT2;4 paralogue can function as a Ca²⁺-permeable cation channel (Lan et al., 2010).