TCDB » SEARCH

« See all members of the family

2.A.39.3.4 Allantoin permease, PucI, with 12 TMSs and both N- and C-termini on the inside. PucI transports allantoin with a Km of 24 mμM, but recognizes some additional hydantoin compounds, including hydantoin itself, and to a lesser extent a range of nucleobases and nucleosides (Ma et al. 2016).
Accession Number:	P94575
Protein Name:	PucI aka YwoE
Length:	490
Molecular Weight:	53982.00
Species:	Bacillus subtilis [1423]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	allantoin

RefSeq:	NP_391528.1
Entrez Gene ID:	936935
Pfam:	PF02133
KEGG:	bsu:BSU36470
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0015205 F:nucleobase transmembrane transporter activity GO:0015931 P:nucleobase, nucleoside, nucleotide and nucl... GO:0055085 P:transmembrane transport
References (3) [1] “The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).” Presecan E.et.al. 9353933 [2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F.et.al. 9384377 [3] “Functional analysis of 14 genes that constitute the purine catabolic pathway in Bacillus subtilis and evidence for a novel regulon controlled by the PucR transcription activator.” Schultz A.C.et.al. 11344136

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKLKESQQQS NRLSNEDLVP LGQEKRTWKA MNFASIWMGC IHNIPTYATV GGLIAIGLSP 
61:	WQVLAIIITA SLILFGALAL NGHAGTKYGL PFPVIIRASY GIYGANIPAL LRAFTAIMWL 
121:	GIQTFAGSTA LNILLLNMWP GWGEIGGEWN ILGIHLSGLL SFVFFWAIHL LVLHHGMESI 
181:	KRFEVWAGPL VYLVFGGMVW WAVDIAGGLG PIYSQPGKFH TFSETFWPFA AGVTGIIGIW 
241:	ATLILNIPDF TRFAETQKEQ IKGQFYGLPG TFALFAFASI TVTSGSQVAF GEPIWDVVDI 
301:	LARFDNPYVI VLSVITLCIA TISVNVAANI VSPAYDIANA LPKYINFKRG SFITALLALF 
361:	TVPWKLMESA TSVYAFLGLI GGMLGPVAGV MMADYFIIRK RELSVDDLYS ETGRYVYWKG 
421:	YNYRAFAATM LGALISLIGM YVPVLKSLYD ISWFVGVLIS FLFYIVLMRV HPPASLAIET 
481:	VEHAQVRQAE

2.A.39.3.4
Allantoin permease, PucI, with 12 TMSs and both N- and C-termini on the inside. PucI transports allantoin with a Km of 24 mμM, but recognizes some additional hydantoin compounds, including hydantoin itself, and to a lesser extent a range of nucleobases and nucleosides (Ma et al. 2016).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

2.A.39.3.4Allantoin permease, PucI, with 12 TMSs and both N- and C-termini on the inside. PucI transports allantoin with a Km of 24 mμM, but recognizes some additional hydantoin compounds, including hydantoin itself, and to a lesser extent a range of nucleobases and nucleosides (Ma et al. 2016).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

2.A.39.3.4
Allantoin permease, PucI, with 12 TMSs and both N- and C-termini on the inside. PucI transports allantoin with a Km of 24 mμM, but recognizes some additional hydantoin compounds, including hydantoin itself, and to a lesser extent a range of nucleobases and nucleosides (Ma et al. 2016).