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2.A.39.3.6 The benzyl-hydantoin:cation symporter-1, Mhp1 (84% identical to 2.A.39.3.5). The 3-d structures in the open and closed states (2.85 Å resolution) are known (Weyand et al., 2008). Models of the ion-coupled coonformational cycle have been proposed (Kazmier et al. 2014).
Accession Number:	D6R8X8
Protein Name:	Hydantoin transport protein
Length:	501
Molecular Weight:	54581.00
Species:	Microbacterium liquefaciens [33918]
Number of TMSs:	12
Substrate	cation, base

Structure:
Pfam:	PF02133
Gene Ontology GO:0016020 C:membrane GO:0015205 F:nucleobase transmembrane transporter activity
References (1) [1] “Molecular basis of alternating access membrane transport by the sodium-hydantoin transporter Mhp1.” Shimamura T.et.al. 20413494
2JLN 2X79 4D1A 4D1B 4D1C 4D1D

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MNSTPIEEAR SLLNPSNAPT RYAERSVGPF SLAAIWFAMA IQVAIFIAAG QMTSSFQVWQ 
61:	VIVAIAAGCT IAVILLFFTQ SAAIRWGINF TVAARMPFGI RGSLIPITLK ALLSLFWFGF 
121:	QTWLGALALD EITRLLTGFT NLPLWIVIFG AIQVVTTFYG ITFIRWMNVF ASPVLLAMGV 
181:	YMVYLMLDGA DVSLGEVMSM GGENPGMPFS TAIMIFVGGW IAVVVSIHDI VKECKVDPNA 
241:	SREGQTKADA RYATAQWLGM VPASIIFGFI GAASMVLVGE WNPVIAITEV VGGVSIPMAI 
301:	LFQVFVLLAT WSTNPAANLL SPAYTLCSTF PRVFTFKTGV IVSAVVGLLM MPWQFAGVLN 
361:	TFLNLLASAL GPLAGIMISD YFLVRRRRIS LHDLYRTKGI YTYWRGVNWV ALAVYAVALA 
421:	VSFLTPDLMF VTGLIAALLL HIPAMRWVAK TFPLFSEAES RNEDYLRPIG PVAPADESAT 
481:	ANTKEQNQPA GGRGSHHHHH H

2.A.39.3.6
The benzyl-hydantoin:cation symporter-1, Mhp1 (84% identical to 2.A.39.3.5). The 3-d structures in the open and closed states (2.85 Å resolution) are known (Weyand et al., 2008). Models of the ion-coupled coonformational cycle have been proposed (Kazmier et al. 2014).

Cross database links:

Gene Ontology

References (1)

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2.A.39.3.6 The benzyl-hydantoin:cation symporter-1, Mhp1 (84% identical to 2.A.39.3.5). The 3-d structures in the open and closed states (2.85 Å resolution) are known (Weyand et al., 2008). Models of the ion-coupled coonformational cycle have been proposed (Kazmier et al. 2014).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.39.3.6
The benzyl-hydantoin:cation symporter-1, Mhp1 (84% identical to 2.A.39.3.5). The 3-d structures in the open and closed states (2.85 Å resolution) are known (Weyand et al., 2008). Models of the ion-coupled coonformational cycle have been proposed (Kazmier et al. 2014).