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|---|---|
| Accession Number: | O14863 |
| Protein Name: | Zinc transporter 4 |
| Length: | 429 |
| Molecular Weight: | 47483.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 5 |
| Location1 / Topology2 / Orientation3: | Endosome membrane1 / Multi-pass membrane protein2 |
| Substrate | zinc(2+) |
Cross database links:
| Entrez Gene ID: | 7782 |
|---|---|
| Pfam: | PF01545 |
| KEGG: | hsa:7782 |
Gene Ontology
GO:0016023
C:cytoplasmic membrane-bounded vesicle
GO:0010008
C:endosome membrane
GO:0016021
C:integral to membrane
GO:0005770
C:late endosome
GO:0005385
F:zinc ion transmembrane transporter activity
GO:0007595
P:lactation
GO:0061088
P:regulation of sequestering of zinc ion
GO:0009636
P:response to toxin
GO:0033189
P:response to vitamin A
GO:0010043
P:response to zinc ion
GO:0055069
P:zinc ion homeostasis
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References (3)[1] “A novel gene involved in zinc transport is deficient in the lethal milk mouse.” Huang L.et.al. 9354792 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAGSGAWKRL KSMLRKDDAP LFLNDTSAFD FSDEAGDEGL SRFNKLRVVV ADDGSEAPER 61: PVNGAHPTLQ ADDDSLLDQD LPLTNSQLSL KVDSCDNCSK QREILKQRKV KARLTIAAVL 121: YLLFMIGELV GGYIANSLAI MTDALHMLTD LSAIILTLLA LWLSSKSPTK RFTFGFHRLE 181: VLSAMISVLL VYILMGFLLY EAVQRTIHMN YEINGDIMLI TAAVGVAVNV IMGFLLNQSG 241: HRHSHSHSLP SNSPTRGSGC ERNHGQDSLA VRAAFVHALG DLVQSVGVLI AAYIIRFKPE 301: YKIADPICTY VFSLLVAFTT FRIIWDTVVI ILEGVPSHLN VDYIKEALMK IEDVYSVEDL 361: NIWSLTSGKS TAIVHIQLIP GSSSKWEEVQ SKANHLLLNT FGMYRCTIQL QSYRQEVDRT 421: CANCQSSSP