2.A.42.1.6 γ-aminobutyric acid (GABA):Na+ symporter (Zhao et al. 2012). The GABA Km is 40 µM, and uptake is inhibited by L-Asn and L-Gln.
|
Accession Number: | Q6M7P5 |
Protein Name: | Permease for amino acids and related compounds, fa |
Length: | 415 |
Molecular Weight: | 43374.00 |
Species: | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) [196627] |
Number of TMSs: | 11 |
Substrate |
sodium(1+), gamma-aminobutyric acid |
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1: MTTESIVAHN AAGTAPQNVS SAKKKYLSVA QGVALIYGTN IGAGVLSLPY AARNGGFLAL
61: VVALLIAGTL TTISMLYIAE VSLRTKKPLQ LSGLAEKYLG QWGRWLVFIA IVVNSVGALI
121: AYASGSGILI GNLTGLPPIV GTLGFFVLGT LIMWKGLHTA SFVEALITTG MATIIIVLCG
181: WTVLGPGISA DNLIVFHPFF IVPIMNLAVF TFLAQYVVPE IARGVNPATP KAVPRAIIIG
241: MVATGVTLAA VPFAALGLLG TGVSEVVTIS WGEALAPVAY YMANAFALLA MFTSFIAIGF
301: TAMRNVLDIG HWPQHGWQRS VAVGLTVLPP LAISLAGLGG FVAALSYAGG FAGAIMSIIP
361: VLLLRNSRKS GDQEPVWKAT WQAHPIFQIL LIVVYSLAFV YSVLAIVGLM PAGWA