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2.A.43.3.1
The Lec15/Lec35 suppressor, SL15, MPDU1 or SLC66A5, of 247 aas and probably 7 TMSs. It is a suppressor of the Lec15 and Lec35 glycosylation mutations (Ware and Lehrman 1998). The human ortholog is 89% identical to this protein. This protein may be required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.

Accession Number:Q60441
Protein Name:MPU1 aka SL15 aka MPDU1
Length:247
Molecular Weight:26543.00
Species:Cricetulus griseus (Chinese hamster) [10029]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate cystine

Cross database links:

Gene Ontology

GO:0016021 C:integral to membrane

References (2)

[1] “Expression cloning of a novel suppressor of the Lec15 and Lec35 glycosylation mutations of Chinese hamster ovary cells.”  Ware F.E.et.al.   8663248
[2] “”  Ware F.E.et.al.   12755100

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAGEADGPFK RVLVPVLLPE KCYDQLFVHW DFLHVPCLKI LLSKGLGLGI VAGSLLVKLP 
61:	QIFKILGAKS AEGLSLQSVM LELVALTGTV IYSITNNFPF SSWGEALFLT LQTITICLLV 
121:	LHYRGDTVKG VALLACYATL LLALLSPLTP LAVVTMLQAS NVPAVVVGKL LQAATNYHNG 
181:	HTGQLSAITV FMLFGGSLAR IFTSVQETGD PLMAGVFVVS SLCNGLIAAQ VLFYWNAKPP 
241:	HKHKKEQ