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2.A.54.1.5
Sideroflexin-5 (SFXN5; SLC56A5) of 342 aas and 5 TMSs in a 1 + 2 + 2 TMS arrangement. The identification and characterization of the human sideroflexin 5 gene, and its high expression in the brain have been reported (Lockhart et al. 2002). It does not appear to be a Parkinson disease protein but may be a citrate transporter. It is 99% identical to the human ortholog.

Accession Number:Q925N0
Protein Name:Sideroflexin-5
Length:342
Molecular Weight:37329.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Mitochondrion membrane1 / Multi-pass membrane protein2
Substrate iron(3+)

Cross database links:

Entrez Gene ID: 94282   
Pfam: PF03820   
KEGG: mmu:94282   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0008324 F:cation transmembrane transporter activity
GO:0055072 P:iron ion homeostasis

References (2)

[1] “The transcriptional landscape of the mammalian genome.”  Carninci P.et.al.   16141072
[2] “A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice.”  Fleming M.D.et.al.   11274051

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MADTATTASA ASAAASAPNA STDAPPFQLG KPRFQQTSFY GRFRHFLDII DPRTLFVTEK 
61:	RLREAVQLLE DYKHGTLRPG VTNEQLWSAQ KIKQAILHPD TNEKIFMPFR MSGYIPFGTP 
121:	IVVGLLLPNQ TLASTVFWQW LNQSHNACVN YANRNATKPS PASKFIQGYL GAVISAVSIA 
181:	VGLNVLVQKA NKFTPATRLL VQRFVPFPAV ASANICNVVL MRYGELEEGI DVLDADGNLV 
241:	GSSKIAARHA LLETALTRVV LPMPILVLPP IVMSMLEKTA LLQARPRLLL PVHSLVCLAA 
301:	FGLALPLAIS LFPQMSEIET SQLEPEIARA TSSRTVVYNK GL