2.A.55.2.13
Enterocyte iron uptake system, NRAMP or DMT1 of 558 aas and 13 TMSs. Inhibited by lead and cadmium ions competitively (Kwong et al. 2010). The close (85% identity) homologue from Scophthalmus maximus (Turbot) (Psetta maxima) has been characterized (Chen et al. 2007).
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| Accession Number: | Q9W666 |
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| Protein Name: | Natural resistance associated macrophage protein-beta |
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| Length: | 558 |
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| Molecular Weight: | 61639.00 |
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| Species: | Oncorhynchus mykiss (Rainbow trout) [8022] |
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| Number of TMSs: | 13 |
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| Substrate |
iron(2+) |
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1: METEREADLL EEEPPQENGV IQSTQGLYSS TSPPASDDEP FSTYFEEKVP IPEDVTQMFS
61: FRKLWAFTGP GFLMSIAYLD PGNIESDLQS GAKAGFKLLW VLLGATIIGL LLQRLAARLG
121: VVTGMHLAEV CNRQYPTVPR IILWLMVELA IIGSDMQEVI GCAIAFNLLS MGRIPLWGGV
181: LITIIDTFVF LFLDKYGLRK LEAFFGFLIT TMAVSFGYEY VMVRPDQGEL LKGMFLPYCE
241: NCDSAQMEQA VGIVGAVIMP HNIYLHSALV KSRQIDRGNK KEVKEANKYY FIESTIALFI
301: SFLINVFVVA VFAEAFYDKT NIEVNAKCNA SGSPHTDLFP LDNSTLQVDI LKGGVVLGCF
361: FGPAALYIWA IGILAAGQSS TMTGTYSGQF VMEGFLNLRW SRFARVLLTR SIAIFPTLLV
421: AIFQDVQHLT GMNDFLNVLQ SMQLPFALIP ILTFTSLTSI MDDFANGLVW KIGGGVVILV
481: VCAINMYFVV VYVTSLNSVA LYVLVALLCI AYLSFVCYLA WQCLIALGVS CLDVSCLGNR
541: VSNNCHAVFI EEQPAYDT