2.A.55.2.19 NRAMP5 of 538 aas and 12 TMSs. Transports Cd2+. Mutations lead to low Cd2+ accumulation in plants and seeds (Cao et al. 2019).
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Accession Number: | Q8H4H5 |
Protein Name: | Metal transporter Nramp5 |
Length: | 538 |
Molecular Weight: | 58498.00 |
Species: | Oryza sativa subsp. japonica (Rice) [39947] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
divalent metal cation, cadmium(2+) |
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1: MEIERESSER GSISWRASAA HDQDAKKLDA DDQLLMKEPA WKRFLAHVGP GFMVSLAYLD
61: PGNLETDLQA GANHRYELLW VILIGLIFAL IIQSLAANLG VVTGRHLAEI CKSEYPKFVK
121: IFLWLLAELA VIAADIPEVI GTAFAFNILF HIPVWVGVLI TGTSTLLLLG LQKYGVRKLE
181: FLISMLVFVM AACFFGELSI VKPPAKEVMK GLFIPRLNGD GATADAIALL GALVMPHNLF
241: LHSALVLSRK TPASVRGIKD GCRFFLYESG FALFVALLIN IAVVSVSGTA CSSANLSQED
301: ADKCANLSLD TSSFLLKNVL GKSSAIVYGV ALLASGQSST ITGTYAGQYI MQGFLDIRMR
361: KWLRNLMTRT IAIAPSLIVS IIGGSRGAGR LIIIASMILS FELPFALIPL LKFSSSKSKM
421: GPHKNSIYII VFSWFLGLLI IGINMYFLST SFVGWLIHND LPKYANVLVG AAVFPFMLVY
481: IVAVVYLTIR KDSVVTFVAD SSLAAVVDAE KADAGDLAVD DDEPLPYRDD LADIPLPR