2.A.55.2.20
NRAMP1 or DMT1 of 513 aas and 11 or 12 putative TMSs. It shows higher similarity to prokaryotic than eukaryotic homologues. The N-terminus displays exclusively prokaryotic characteristics. Functional complementation experiments revealed that DMT1 has a broad specificity, transporting several divalent metals (manganese, iron, cadmium and copper), but not zinc (Rosakis and Köster 2005).
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| Accession Number: | Q8LKG7 |
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| Protein Name: | Manganese transport protein |
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| Length: | 513 |
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| Molecular Weight: | 54712.00 |
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| Species: | Chlamydomonas reinhardtii [3055] |
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| Number of TMSs: | 11 |
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| Substrate |
divalent metal cation, cadmium(2+), copper cation, iron cation, manganese(2+) |
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1: MVLGRLFARS ESAAPALADY NNEGNGSTID TSVVAVEVEA SGSPSSATVR GDSTLNEPLL
61: EGFKDRGELP SLPESNASLS FPEESAPWWR KFFAFMGLGF LISVGYMDPG NWATDLAAGS
121: SFGYTLLFVV LCSSLCAMFL QYLSLKLGIA SDRDLAQACR DAYHPHVNKL LWVVAEAAIA
181: ATDLAEVVGC AIAFNLLLGI PLWAGVLITA ADVIILLVAE ARSFRFLEIL VGALTALISA
241: CFIYELVKAQ PDMGKVMRGY LPSKEIITNK DMLYLATGIL GATVMPHNLY LHSSVIQTRA
301: YPRTTAGRTI AIKLGLVDST LSLLVAFVIN SSILIVAAAA FHYATPPLED IADITDAYEL
361: LASSLGSKAA SILFGVALLA AGQNSTITGT LSGQIVMEGF LSFKMRPWLR RIITRGAAIV
421: PAATVAAVMG REGVSQLLVL SQVILSLTLP FAVFPLVHFT SSRKYLGNFA NRWYASVIAW
481: LLFLFISALN VNLVVQSAIS GSFGGLGHRR AAV